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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
cyclin and CBS domain divalent metal cation transport mediator 2
Summary
- Gene Symbol
-
- Cnnm2
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- CBS domain
- Cell membrane
- Glycoprotein
- Ion transport
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A8I5ZZS9 |
|
| Q5U2P1 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane transport | ||
| magnesium ion transport | ||
| monoatomic ion transport | ||
| ion transport | ||
| magnesium ion homeostasis |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| basolateral plasma membrane | ||
| synapse | ||
| glutamatergic synapse |
| GO Term | Evidence Code | PMID |
|---|---|---|
| magnesium ion transmembrane transporter activity | ||
| ATP binding | ||
| transmembrane transporter activity |
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- metal transporter CNNM2
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- P: Inorganic ion transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| intracellular manganese ion homeostasis |
| magnesium ion homeostasis |
| magnesium ion transmembrane transporter activity |
| InterPro |
|---|
| Ancient conserved domain protein family |
| CBS domain superfamily |
| CNNM, transmembrane domain |
| Ion transporter-like, CBS domain |
| RmlC-like jelly roll fold |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060884 | renal hypomagnesemia 6 | |
| DOID:5419 | schizophrenia |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 54805 | HGNC:103 | HUMAN02797 | ||
| 94219 | 10090_1:005312 | MGI:2151054 | MOUSE26580 | |
| 178499 | WB:WBGene00016879 | |||
| 180591 | WB:WBGene00016343 | |||
| 450705 | PANTR01473 | |||
| 486866 | CANLF11439 | |||
| 504632 | BOVIN21450 | |||
| 555472 | ZFIN:ZDB-GENE-050208-36 | DANRE05689 | ||
| 565702 | ZFIN:ZDB-GENE-090311-26 | DANRE18387 | ||
| 714238 | MACMU46522 |
