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solute carrier family 3 member 1

Summary

Gene Symbol

Slc3a1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29484

PubChem

29484

Alliance of Genome Resources

RGD:3709

Annotation

Keyword

Amino-acid transport
Calcium
Cell membrane
Disulfide bond
Glycoprotein
Metal-binding
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q64319	D2 Neutral and basic amino acid transport protein Solute carrier family 3 member 1 b(0,+)-type amino acid transporter-related heavy chain
A6H9H4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
L-glutamate transmembrane transport	ISO
L-cystine transport	ISO
aspartate transmembrane transport	ISO
amino acid transport	IBA IDA	1376924
carbohydrate metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport [inference]

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport

sulfur amino acid transport [inference]

L-cystine transport

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

neutral amino acid transport [inference]

L-cystine transport

L-amino acid transport [inference]

L-cystine transport

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

dicarboxylic acid transport [inference]

C4-dicarboxylate transport [inference]

aspartate transmembrane transport

L-glutamate import [inference]

L-glutamate transmembrane transport

amino acid transport

sulfur amino acid transport [inference]

L-cystine transport

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

neutral amino acid transport [inference]

L-cystine transport

L-amino acid transport [inference]

L-cystine transport

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

modified amino acid transport [inference]

L-cystine transport

nitrogen compound transport [inference]

amino acid transport

sulfur amino acid transport [inference]

L-cystine transport

amino acid transmembrane transport [inference]

aspartate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

acidic amino acid transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

neutral amino acid transport [inference]

L-cystine transport

L-amino acid transport [inference]

L-cystine transport

L-glutamate import [inference]

L-glutamate transmembrane transport

L-alpha-amino acid transmembrane transport [inference]

L-glutamate transmembrane transport

amide transport [inference]

L-glutamate import [inference]

L-glutamate transmembrane transport

modified amino acid transport [inference]

L-cystine transport

sulfur compound transport [inference]

sulfur amino acid transport [inference]

L-cystine transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
apical plasma membrane	ISO
vacuolar membrane	IDA	9987991
brush border membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein-containing complex binding	IDA	7628645
metal ion binding	IEA
protein heterodimerization activity	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein dimerization activity [inference]

protein heterodimerization activity

ion binding [inference]

cation binding [inference]

metal ion binding

protein-containing complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Glycosyl hydrolase, family 13, catalytic domain

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
glucan 1,4-alpha-maltotriohydrolase activity
maltose alpha-glucosidase activity
maltose catabolic process
oligo-1,6-glucosidase activity
sucrose alpha-glucosidase activity
sucrose catabolic process

Displaying **all 4** entries
InterPro
Glycoside hydrolase superfamily
Glycosyl hydrolase, all-beta
Glycosyl hydrolase, family 13, catalytic domain
Oligo-1,6-glucosidase, domain 2

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
vacuolar membrane	PMID:9987991

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9266	cystinuria	Alliance of Genome Resources

Ortholog

Displaying entries **31 - 40** of **140** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Sus scrofa	100144588		PIGXX22152
Ciona intestinalis	100185923		CIOIN12491
Salmo salar	100380841		SALSA100564
Callithrix jacchus	100401185		CALJA11394
Ailuropoda melanoleuca	100467387		AILME19639
Anolis carolinensis	100554178		ANOCA16945
Nomascus leucogenys	100600366		NOMLE16537
Loxodonta africana	100662221		LOXAF08482
Cavia porcellus	100726402	10141_0:003253	CAVPO09726
Cricetulus griseus	100765887	10029_0:003842	CRIGR01718

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OrthoDB (Group)

International Collaboration

Acknowledgements