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solute carrier family 10 member 2

Summary

Gene Symbol

Slc10a2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29500

PubChem

29500

Alliance of Genome Resources

RGD:3682

Annotation

Keyword

Glycoprotein
Lipid transport
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q62633	Apical sodium-dependent bile acid transporter Ileal Na(+)/bile acid cotransporter Ileal sodium-dependent bile acid transporter Na(+)-dependent ileal bile acid transporter Sodium/taurocholate-cotransporting polypeptide, ileal Solute carrier family 10 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
sodium ion transport	TAS	11509565
bile acid metabolic process	TAS	15304498
response to bacterium	ISO
bile acid and bile salt transport	IDA	8770054
bile acid and bile salt transport	IBA

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

lipid metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

bile acid metabolic process

organic hydroxy compound metabolic process [inference]

bile acid metabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

bile acid metabolic process

transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteasome complex	IDA	15304498
microvillus	ISO
apical plasma membrane	ISO
apical plasma membrane	IDA	8770054
apical plasma membrane	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

proteasome complex

catalytic complex [inference]

peptidase complex [inference]

endopeptidase complex [inference]

proteasome complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

actin-based cell projection [inference]

microvillus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
bile acid:sodium symporter activity	TAS	11509565
bile acid:sodium symporter activity	IDA	8770054
bile acid:sodium symporter activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity [inference]

bile acid:sodium symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sodium/bile acid cotransporter

Functional Category

P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
bile acid

Displaying **all 3** entries
InterPro
Bile acid
Bile acid
Sodium/solute symporter superfamily

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
apical plasma membrane	PMID:8770054
proteasome complex	PMID:15304498

Ortholog

Displaying entries **1 - 10** of 88 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6555	Xenbase:XB-GENE-982718	HUMAN17594
Caenorhabditis elegans	20493	WB:WBGene00044650
Mus musculus	20494	Xenbase:XB-GENE-982718	MOUSE59604
Caenorhabditis elegans	24777	WB:WBGene00044650
Xenopus tropicalis	29500	Xenbase:XB-GENE-982718
Caenorhabditis elegans	75750	WB:WBGene00044650
Caenorhabditis elegans	231290	WB:WBGene00044650
Drosophila melanogaster	241877	FB:FBgn0030638
Caenorhabditis elegans	289459	WB:WBGene00044650
Caenorhabditis elegans	305309	WB:WBGene00044650