prostaglandin-endoperoxide synthase 2
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of apoptotic process | ||
| negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
|
|
| positive regulation of nitric oxide biosynthetic process | ||
| negative regulation of cell cycle | ||
| positive regulation of vasoconstriction |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleus | ||
| nuclear inner membrane | ||
| nuclear inner membrane | ||
| nuclear outer membrane | ||
| nuclear outer membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| heme binding | ||
| protein homodimerization activity | ||
| metal ion binding |
| Gene Ontology |
|---|
| cellular oxidant detoxification |
| heme binding |
| metal ion binding |
| response to oxidative stress |
| InterPro |
|---|
| Haem peroxidase domain superfamily, animal type |
| Haem peroxidase superfamily |
| Haem peroxidase, animal-type |
| Location | References |
|---|---|
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080322 | polycystic kidney disease | |
| DOID:0080855 | Parkinsonism | |
| DOID:10247 | pleurisy | |
| DOID:10652 | Alzheimer's disease | |
| DOID:10762 | portal hypertension | |
| DOID:10763 | hypertension | |
| DOID:10808 | gastric ulcer | |
| DOID:1184 | nephrotic syndrome | |
| DOID:12466 | secondary hyperparathyroidism | |
| DOID:12858 | Huntington's disease |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5743 | Xenbase:XB-GENE-482133 | HUMAN53922 | |
| 19225 | Xenbase:XB-GENE-482133 | MOUSE30634 | |
| 29527 | Xenbase:XB-GENE-482133 | ||
| 282023 | BOVIN08804 | ||
| 397590 | PIGXX36727 | ||
| 442942 | CANLF17195 | ||
| 443460 | SHEEP03983 | ||
| 469616 | PANTR23233 | ||
| 559020 | DANRE19531 | ||
| 716671 | MACMU22694 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025