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anti-Mullerian hormone receptor type 2

Summary

Gene Symbol

Amhr2

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

29530

PubChem

29530

Alliance of Genome Resources

RGD:70964

Annotation

Keyword

ATP-binding
Disulfide bond
Glycoprotein
Magnesium
Manganese
Metal-binding
Receptor
Reference proteome
Serine/threonine-protein kinase
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q62893	Anti-Muellerian hormone type II receptor C14 MIS type II receptor
A6KCV2	Anti-Muellerian hormone type II receptor MIS type II receptor

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
transforming growth factor beta receptor signaling pathway	IDA	11376112
protein phosphorylation	IEA
male gonad development	IEP	8119126
anti-Mullerian hormone signaling pathway	ISO ISS
sex differentiation	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway

transforming growth factor beta receptor superfamily signaling pathway [inference]

anti-Mullerian hormone signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

reproductive process [inference]

developmental process involved in reproduction [inference]

sex differentiation

reproductive structure development [inference]

gonad development [inference]

developmental process [inference]

developmental process involved in reproduction [inference]

sex differentiation

reproductive structure development [inference]

gonad development [inference]

anatomical structure development [inference]

blood vessel development

animal organ development [inference]

gonad development [inference]

reproductive structure development [inference]

gonad development [inference]

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway

transforming growth factor beta receptor superfamily signaling pathway [inference]

anti-Mullerian hormone signaling pathway

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
receptor complex	IBA
plasma membrane	IBA IDA ISO	11376112

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
hormone binding	ISO ISS
transforming growth factor beta receptor activity	IBA IEA
transforming growth factor beta receptor activity, type II	IDA ISO	11376112
metal ion binding	IEA
anti-Mullerian hormone receptor activity	ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

hormone binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein serine/threonine kinase activity [inference]

transforming growth factor beta receptor activity

transforming growth factor beta receptor activity, type II

protein-hormone receptor activity [inference]

anti-Mullerian hormone receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

anti-Muellerian hormone type-2 receptor

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
kinase activity
metal ion binding
nucleotide binding
phosphorylation
transferase activity
transforming growth factor beta receptor activity
transmembrane receptor protein serine/threonine kinase activity
transmembrane receptor protein serine/threonine kinase signaling pathway

Displaying **all 6** entries
InterPro
Anti-muellerian hormone receptor, type II
Protein kinase domain
Protein kinase-like domain superfamily
Ser/Thr protein kinase, TGFB receptor
Serine-threonine/tyrosine-protein kinase, catalytic domain
Snake toxin-like superfamily

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0050791	persistent Mullerian duct syndrome	Alliance of Genome Resources
DOID:1967	leiomyosarcoma	Alliance of Genome Resources
DOID:4441	dysgerminoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	269		HGNC:465	HUMAN12975
Mus musculus	110542	10090_1:0048e6	MGI:105062	MOUSE16926
Pan troglodytes	467005			PANTR05730
Bos taurus	514963			BOVIN29065
Macaca mulatta	702822			MACMU05401
Oryctolagus cuniculus	100009599			RABIT10397
Sus scrofa	100154297			PIGXX25435
Callithrix jacchus	100408187			CALJA45073
Pongo abelii	100441106			PONAB04744
Ailuropoda melanoleuca	100475241			AILME08700