pyruvate dehydrogenase E1 subunit alpha 1
| UniProt | Protein Name |
|---|---|
| Q4FZZ4 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| glucose metabolic process | ||
| acetyl-CoA biosynthetic process from pyruvate | ||
| acetyl-CoA biosynthetic process from pyruvate | ||
| acetyl-CoA biosynthetic process from pyruvate | ||
| acetyl-CoA biosynthetic process from pyruvate |
| GO Term | Evidence Code | PMID |
|---|---|---|
| nucleolus | ||
| mitochondrion | ||
| mitochondrial matrix | ||
| intracellular membrane-bounded organelle | ||
| pyruvate dehydrogenase complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| pyruvate dehydrogenase activity | ||
| pyruvate dehydrogenase (acetyl-transferring) activity | ||
| pyruvate dehydrogenase (acetyl-transferring) activity | ||
| pyruvate dehydrogenase (acetyl-transferring) activity | ||
| pyruvate dehydrogenase (acetyl-transferring) activity |
| InterPro |
|---|
| Dehydrogenase, E1 component |
| Thiamin diphosphate-binding fold |
| Location | References |
|---|---|
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3649 | pyruvate decarboxylase deficiency |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5160 | Xenbase:XB-GENE-952669 | HUMAN99960 | |
| 5161 | Xenbase:XB-GENE-952669 | ||
| 18597 | Xenbase:XB-GENE-952669 | MOUSE65522 | |
| 18598 | Xenbase:XB-GENE-952669 | ||
| 29554 | Xenbase:XB-GENE-952669 | ||
| 117098 | Xenbase:XB-GENE-952669 | ||
| 406702 | DANRE37248 | ||
| 407109 | BOVIN37381 | ||
| 465525 | PANTR45605 | ||
| 100014220 | MONDO21692 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025