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hypoxia inducible lipid droplet associated

Summary

Gene Symbol

HILPDA

Organism

Homo sapiens (human)

External Links

NCBI Gene

29923

PubChem

29923

Alliance of Genome Resources

HGNC:28859

Annotation

Keyword

Lipid droplet
Phosphoprotein
Reference proteome
Secreted
Stress response
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9Y5L2	Hypoxia-inducible gene 2 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
positive regulation of cytokine production	IDA	20624928
positive regulation of cell population proliferation	IDA	15930302
positive regulation of lipid storage	IDA	20624928
autocrine signaling	IDA	15930302
autocrine signaling	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

autocrine signaling

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to stimulus [inference]

response to stress [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to stress [inference]

cellular response to hypoxia

response to abiotic stimulus [inference]

response to oxygen levels [inference]

response to decreased oxygen levels [inference]

response to hypoxia [inference]

cellular response to hypoxia

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

response to chemical [inference]

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to hypoxia

cellular response to chemical stimulus [inference]

cellular response to oxygen levels [inference]

cellular response to decreased oxygen levels [inference]

cellular response to hypoxia

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

signaling [inference]

cell-cell signaling [inference]

autocrine signaling

regulation of localization [inference]

regulation of lipid storage [inference]

positive regulation of lipid storage

regulation of lipid localization [inference]

positive regulation of lipid localization [inference]

positive regulation of lipid storage

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

positive regulation of lipid localization [inference]

positive regulation of lipid storage

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of gene expression [inference]

positive regulation of cytokine production

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

positive regulation of cytokine production

positive regulation of multicellular organismal process [inference]

positive regulation of cytokine production

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
extracellular space	IDA	15930302
nucleoplasm	IDA
lipid droplet	IDA	20624928
lipid droplet	IBA
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular non-membrane-bounded organelle [inference]

lipid droplet

Displaying **all 2** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IPI	15930302
protein binding	IPI	15930302 25416956

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

hypoxia-inducible lipid droplet-associated protein

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
M: Cell wall/membrane/envelope biogenesis

Displaying **all 3** entries
Gene Ontology
autocrine signaling
positive regulation of cell population proliferation
positive regulation of lipid storage

Displaying 1 entry
InterPro
Hypoxia-inducible lipid droplet-associated protein

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:684	hepatocellular carcinoma	Alliance of Genome Resources
DOID:9256	colorectal cancer	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 19 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Rattus norvegicus	29923	RGD:2319900
Mus musculus	69573		MOUSE49964
Pan troglodytes	463702		PANTR41340
Oryctolagus cuniculus	100356441		RABIT11451
Nomascus leucogenys	100592190		NOMLE06300
Cavia porcellus	100728448		CAVPO06168
Cricetulus griseus	100750353		CRIGR03478
Pan paniscus	100981679		PANPA37132
Gorilla gorilla gorilla	101134012		GORGO37689
Heterocephalus glaber	101720002		HETGA01523