GlyCosmos Portal

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
peptide receptor activity	IBA
adenylate cyclase activity
guanylate cyclase activity	TAS
guanylate cyclase activity	IDA	21928830 30319355
guanylate cyclase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

cyclase activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

lyase activity [inference]

phosphorus-oxygen lyase activity [inference]

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

protein-containing complex binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

guanyl nucleotide binding [inference]

guanyl ribonucleotide binding [inference]

GTP binding

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

purine ribonucleoside triphosphate binding [inference]

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

guanyl ribonucleotide binding [inference]

GTP binding

molecular transducer activity [inference]

signaling receptor activity

peptide receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Guanylate cyclase

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
adenylate cyclase activity
cGMP biosynthetic process
cyclic nucleotide biosynthetic process
guanylate cyclase activity
lyase activity
peptide receptor activity
phosphorus-oxygen lyase activity
receptor guanylyl cyclase signaling pathway

Displaying **all 8** entries
InterPro
Adenylyl cyclase class-3/4/guanylyl cyclase
Adenylyl cyclase class-4/guanylyl cyclase, conserved site
Nucleotide cyclase
Periplasmic binding protein-like I
Protein kinase domain
Protein kinase-like domain superfamily
Receptor, ligand binding region
Serine-threonine/tyrosine-protein kinase, catalytic domain

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0050534	congenital stationary night blindness	Alliance of Genome Resources
DOID:0110078	Leber congenital amaurosis 1	Alliance of Genome Resources
DOID:0111011	cone-rod dystrophy 6	Alliance of Genome Resources
DOID:10584	retinitis pigmentosa	Alliance of Genome Resources
DOID:980	choroidal sclerosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 46 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	3000	Xenbase:XB-GENE-1014102
Mus musculus	14919	Xenbase:XB-GENE-1014102	MOUSE05504
Rattus norvegicus	79222	Xenbase:XB-GENE-1014102	RATNO02478
Danio rerio	113911	ZFIN:ZDB-GENE-011128-7
Bos taurus	282245		BOVIN12783
Canis lupus familiaris	403863		CANLF15476
Macaca mulatta	716734		MACMU14784
Pan troglodytes	750641		PANTR13531
Monodelphis domestica	100014788		MONDO12863
Oryctolagus cuniculus	100344095		RABIT07182

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements