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wingless-type MMTV integration site family, member 5b

Summary

Gene Symbol

wnt5b

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

30105

PubChem

30105

Alliance of Genome Resources

ZFIN:ZDB-GENE-980526-87

Annotation

Keyword

Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Reference proteome
Signal
Transmembrane helix
Wnt signaling pathway

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8M6Z5V6
B3DI33
Q92050

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 38 in total

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GO Term	Evidence Code	PMID
lymphangiogenesis	IMP	25992545
thrombocyte differentiation	IMP	22308195
neuron differentiation	IBA
animal organ development	IEA
cartilage morphogenesis	IMP	26459057 27908786

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, calcium modulating pathway

canonical Wnt signaling pathway

cell growth [inference]

unidimensional cell growth

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

myeloid cell differentiation [inference]

thrombocyte differentiation

cell fate commitment

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration

cell migration involved in gastrulation

dorsal convergence

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

multicellular organismal process [inference]

ossification

replacement ossification [inference]

endochondral ossification

developmental process [inference]

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

unidimensional cell growth

lymphangiogenesis

animal organ morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

skeletal system morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

cartilage morphogenesis

body morphogenesis [inference]

embryonic body morphogenesis

post-anal tail morphogenesis

embryonic morphogenesis [inference]

embryonic organ morphogenesis [inference]

embryonic skeletal system morphogenesis [inference]

embryonic cranial skeleton morphogenesis

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

convergent extension

cartilage morphogenesis

anatomical structure formation involved in morphogenesis [inference]

anatomical structure development [inference]

tissue development [inference]

epithelium development [inference]

somite development

endocrine pancreas development

regeneration [inference]

tissue regeneration [inference]

fin regeneration

animal organ development

sensory organ development [inference]

neuromast development

system development [inference]

skeletal system development

otolith development

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

myeloid cell differentiation [inference]

thrombocyte differentiation

cell fate commitment

growth [inference]

cell growth [inference]

unidimensional cell growth

developmental growth [inference]

tissue regeneration [inference]

fin regeneration

developmental growth involved in morphogenesis [inference]

unidimensional cell growth

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular sphingolipid homeostasis

lipid homeostasis [inference]

intracellular sphingolipid homeostasis

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

organic substance transport [inference]

calcium ion transport [inference]

calcium ion transmembrane transport [inference]

calcium ion transmembrane import into cytosol [inference]

release of sequestered calcium ion into cytosol

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of localization [inference]

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of developmental process [inference]

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of convergent extension involved in gastrulation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of morphogenesis of an epithelium [inference]

regulation of convergent extension involved in gastrulation [inference]

positive regulation of convergent extension involved in gastrulation

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of convergent extension involved in gastrulation

positive regulation of developmental process [inference]

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of convergent extension involved in gastrulation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

non-canonical Wnt signaling pathway [inference]

Wnt signaling pathway, calcium modulating pathway

canonical Wnt signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

regulation of non-canonical Wnt signaling pathway [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Wnt signaling pathway [inference]

positive regulation of non-canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of sequestering of calcium ion [inference]

negative regulation of sequestering of calcium ion [inference]

release of sequestered calcium ion into cytosol

regulation of molecular function [inference]

positive regulation of molecular function [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of serine C-palmitoyltransferase activity

regulation of catalytic activity [inference]

positive regulation of catalytic activity [inference]

positive regulation of transferase activity [inference]

positive regulation of serine C-palmitoyltransferase activity

regulation of transferase activity [inference]

positive regulation of transferase activity [inference]

positive regulation of serine C-palmitoyltransferase activity

regulation of serine C-palmitoyltransferase activity [inference]

positive regulation of serine C-palmitoyltransferase activity

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	IEA
extracellular region	IEA
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IEA IPI	20660632
frizzled binding	IBA
cytokine activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

G protein-coupled receptor binding [inference]

frizzled binding

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
plasma membrane	PMID:25934698

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:127	leiomyoma	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 71 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	22419	MGI:98959	MOUSE50762
Drosophila melanogaster	32838	FB:FBgn0010194
Homo sapiens	81029	HGNC:16265	HUMAN10406
Caenorhabditis elegans	177870	WB:WBGene00000858
Rattus norvegicus	282582	RGD:628850	RATNO29667
Ciona intestinalis	445761		CIOIN15190
Xenopus tropicalis	448452	Xenbase:XB-GENE-480396
Pan troglodytes	467191		PANTR04820
Bos taurus	508008		BOVIN30585
Macaca mulatta	721685		MACMU04635

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Acknowledgements