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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 3
Summary
- Gene Symbol
-
- gdf3
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Growth factor
- Mitogen
- Proteomics identification
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P35621 |
|
| A0A8M9PNK2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| regulation of nodal signaling pathway | ||
| positive regulation of cell division | ||
| regulation of epiboly involved in gastrulation with mouth forming second | ||
| heart looping | ||
| left/right pattern formation |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Bone morphogenetic protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050545 | visceral heterotaxy | |
| DOID:0060772 | multiple types of congenital heart defects 6 | |
| DOID:0060838 | isolated microphthalmia 7 | |
| DOID:0060850 | annular pancreas | |
| DOID:0080591 | Klippel-Feil syndrome 3 | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:1682 | congenital heart disease | |
| DOID:5082 | liver cirrhosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2657 | HGNC:4214 | |||
| 9573 | HGNC:4218 | |||
| 14559 | MGI:95683 | |||
| 14562 | MGI:95686 | |||
| 493288 | Xenbase:XB-GENE-487309 | |||
| 500311 | RGD:1564178 | |||
| 549573 | Xenbase:XB-GENE-481419 | |||
| 100696395 | 8128_0:004587 | ORENI21490 | ||
| 101069811 | 31033_0:00014a | TAKRU25651 | ||
| 101155973 | 8090_0:004a26 | ORYLA09458 |
