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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
growth differentiation factor 3
Summary
- Gene Symbol
-
- gdf3
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Growth factor
- Mitogen
- Proteomics identification
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P35621 |
|
| A0A8M9PNK2 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neuron development | ||
| axis specification | ||
| convergent extension involved in gastrulation | ||
| BMP signaling pathway | ||
| nodal signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein-containing complex | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| growth factor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Bone morphogenetic protein
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cytokine activity |
| growth factor activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050545 | visceral heterotaxy | |
| DOID:0060772 | multiple types of congenital heart defects 6 | |
| DOID:0060838 | isolated microphthalmia 7 | |
| DOID:0060850 | annular pancreas | |
| DOID:0080591 | Klippel-Feil syndrome 3 | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:1682 | congenital heart disease | |
| DOID:5082 | liver cirrhosis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 105930320 | 8078_0:001917 | |||
| 106511345 | 52670_0:0058a6 | |||
| 106582479 | 8030_0:0084d0 | SALSA77731 | ||
| 107097387 | 28743_0:003e1b | |||
| 107389681 | 105023_0:0029a3 | |||
| 107552892 | 75366_0:0061b6 | SINGR62771 | ||
| 107663137 | 1608454_0:006c91 | |||
| 107737894 | 307959_0:001497 | |||
| 107740853 | 307959_0:0002e3 | |||
| 108238824 | 37003_0:00178d |
