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wingless-type MMTV integration site family, member 1

Summary

Gene Symbol

wnt1

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

30128

PubChem

30128

Alliance of Genome Resources

ZFIN:ZDB-GENE-980526-526

Annotation

Keyword

Developmental protein
Differentiation
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Neurogenesis
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8M2B987
B3DI55
P24257

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
nervous system development	IEA
Wnt signaling pathway	IEA
cerebellum morphogenesis	IMP	18423594
fourth ventricle development	IMP	18191121
cell differentiation	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

cellular developmental process [inference]

cell differentiation

neuron differentiation

cell fate commitment

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

segmentation [inference]

brain segmentation

developmental process [inference]

anatomical structure morphogenesis [inference]

cerebellum morphogenesis

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation

neuron differentiation

cell fate commitment

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IEA
frizzled binding	IBA
cytokine activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding

G protein-coupled receptor binding [inference]

frizzled binding

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Wnt

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
canonical Wnt signaling pathway
cell fate commitment
cytokine activity
neuron differentiation
signaling receptor binding

Displaying **all 3** entries
InterPro
Wnt protein, conserved site
Wnt, C-terminal domain
Wnt

Ortholog

Displaying entries **1 - 10** of 72 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	7471	Xenbase:XB-GENE-485280	HUMAN12394
Mus musculus	22408	Xenbase:XB-GENE-485280	MOUSE16280
Rattus norvegicus	24881		RATNO38410
Xenopus tropicalis	30128	Xenbase:XB-GENE-485280
Xenopus tropicalis	34009	Xenbase:XB-GENE-485280
Drosophila melanogaster	173399	FB:FBgn0284084
Xenopus tropicalis	373578	Xenbase:XB-GENE-485280
Canis lupus familiaris	486560		CANLF10849
Bos taurus	540662		BOVIN29272
Macaca mulatta	709009		MACMU04080