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MIRAGE
hydroxysteroid 17-beta dehydrogenase 10

Summary
Gene Symbol
  • HSD17B10
Organism
Homo sapiens (human)
NCBI Gene
3028
PubChem
3028
Alliance of Genome Resources
JoGo
HSD17B10
TogoVar
HSD17B10
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Alternative splicing
  • Disease variant
  • Fatty acid metabolism
  • Intellectual disability
  • Mitochondrion nucleoid
  • NAD
  • Neurodegeneration
  • Oxidoreductase
  • Proteomics identification
  • Reference proteome
  • Steroid metabolism
  • tRNA processing
Proteins
Displaying all 2 entries
UniProt Protein Name
Q99714
  • 17-beta-estradiol 17-dehydrogenase
  • 2-methyl-3-hydroxybutyryl-CoA dehydrogenase
  • 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • 3-hydroxyacyl-CoA dehydrogenase type II
  • 3alpha(or 20beta)-hydroxysteroid dehydrogenase
  • 7-alpha-hydroxysteroid dehydrogenase
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • Mitochondrial ribonuclease P protein 2
  • Short chain dehydrogenase/reductase family 5C member 1
  • Short-chain type dehydrogenase/reductase XH98G2
  • Type II HADH
A0A0S2Z410
  • 17-beta-estradiol 17-dehydrogenase
  • 2-methyl-3-hydroxybutyryl-CoA dehydrogenase
  • 3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))
  • 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • 3-hydroxyacyl-CoA dehydrogenase type II
  • 3alpha(or 20beta)-hydroxysteroid dehydrogenase
  • 7-alpha-hydroxysteroid dehydrogenase
  • Endoplasmic reticulum-associated amyloid beta-peptide-binding protein
  • Mitochondrial ribonuclease P protein 2
  • Short chain dehydrogenase/reductase family 5C member 1
  • Short-chain type dehydrogenase/reductase XH98G2
  • Type II HADH
Annotation information from UniProt.
Gene Ontology (GO)
Displaying entries 1 - 5 of 19 in total
GO Term Evidence Code PMID
isoleucine catabolic process
isoleucine catabolic process
lipid metabolic process
fatty acid metabolic process
fatty acid beta-oxidation
GO Hierarchy
Displaying entries 1 - 5 of 12 in total
GO Term Evidence Code PMID
cytoplasm
mitochondrion
mitochondrion
mitochondrion
mitochondrion
GO Hierarchy
Displaying entries 1 - 5 of 14 in total
GO Term Evidence Code PMID
tRNA binding
RNA binding
3-hydroxyacyl-CoA dehydrogenase activity
estradiol 17-beta-dehydrogenase [NAD(P)] activity
protein binding
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
Disease
Disease Ontology
Displaying all 2 entries
DO ID Disease Name Source
DOID:0050771 pheochromocytoma
DOID:0060810 syndromic X-linked intellectual disability type 10
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026