hexosaminidase subunit alpha
| UniProt | Protein Name |
|---|---|
| A0A0S2Z3W3 |
|
| P06865 |
|
| B4DVA7 |
|
| H3BP20 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| skeletal system development | ||
| carbohydrate metabolic process | ||
| glycosaminoglycan biosynthetic process | ||
| N-glycan processing | ||
| ganglioside catabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| lysosomal lumen | ||
| lysosomal lumen | ||
| intracellular membrane-bounded organelle | ||
| extracellular exosome | ||
| beta-N-acetylhexosaminidase complex |
| GO Term | Evidence Code | PMID |
|---|---|---|
| beta-N-acetylhexosaminidase activity | ||
| beta-N-acetylhexosaminidase activity | ||
| beta-N-acetylhexosaminidase activity | ||
| protein binding | ||
| acetylglucosaminyltransferase activity |
| Gene Ontology |
|---|
| beta-N-acetylhexosaminidase activity |
| glycosaminoglycan metabolic process |
| hydrolase activity, acting on glycosyl bonds |
| hydrolase activity |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:3320 | Tay-Sachs disease |
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000618 | Blindness |
| HP:0000726 | Dementia |
| HP:0000741 | Apathy |
| HP:0000980 | Pallor |
| HP:0001250 | Seizure |
| HP:0001252 | Hypotonia |
| HP:0001276 | Hypertonia |
| HP:0001290 | Generalized hypotonia |
| HP:0002267 | Exaggerated startle response |
| Disease ID | Disease Name |
|---|---|
| OMIM:272800 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 3073 | ZFIN:ZDB-GENE-050417-283 | ||
| 3074 | FB:FBgn0045063 | ||
| 15211 | ZFIN:ZDB-GENE-050417-283 | MOUSE62474 | |
| 15212 | FB:FBgn0045063 | ||
| 31808 | ZFIN:ZDB-GENE-050417-283 | ||
| 38528 | ZFIN:ZDB-GENE-050417-283 | ||
| 180533 | ZFIN:ZDB-GENE-050417-283 | ||
| 250735 | ZFIN:ZDB-GENE-050417-283 | ||
| 294673 | FB:FBgn0045063 | ||
| 300757 | ZFIN:ZDB-GENE-050417-283 | RATNO42149 |
GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.
Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
GlyCosmos Portal v4.4.0
Last updated: December 8, 2025