GlyCosmos Portal

Submissions

interleukin-10

Summary

Gene Symbol

UL111A

Organism

Human betaherpesvirus 5

External Links

NCBI Gene: 3077506
PubChem: 3077506

Annotation

Keyword

Cytokine
Disulfide bond
Evasion of host immunity by viral interleukin-like protein
Glycoprotein
Inhibition of host interferon signaling pathway by virus
Modulation of host dendritic cell activity by virus
Reference proteome
Secreted
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9J4B7
B9VXR2
F5HC71

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
immune response
suppression by virus of host type I interferon-mediated signaling pathway
evasion by virus of host dendritic cell activity
suppression of host innate immune response

GO Hierarchy

biological process

immune system process [inference]

immune response

viral process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

biological process involved in interspecies interaction between organisms [inference]

modulation of process of another organism [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

modulation by symbiont of host process [inference]

modulation by virus of host process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

modulation by symbiont of host cellular process [inference]

modulation by virus of host cellular process [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to stimulus [inference]

immune response

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to defenses of other organism [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host [inference]

response to host defenses [inference]

perturbation of host defenses by symbiont [inference]

suppression of host defenses by symbiont [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host defense response [inference]

virus-mediated perturbation of host defense response [inference]

evasion by virus of host dendritic cell activity

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

response to host immune response [inference]

symbiont-mediated perturbation of host immune response [inference]

perturbation of host innate immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

suppression by symbiont of host immune response [inference]

suppression of host innate immune response

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

perturbation by virus of host immune response [inference]

suppression by virus of host innate immune response [inference]

suppression of host interferon-mediated signaling pathway [inference]

suppression by virus of host type I interferon-mediated signaling pathway

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying 1 entry
GO Term	Evidence Code	PMID
cytokine activity

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

receptor ligand activity [inference]

cytokine activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level: Viruses
Group Name: Interleukin-10

Displaying **all 2** entries
Gene Ontology
cytokine activity
immune response

Displaying **all 3** entries
InterPro
Four-helical cytokine-like, core
Interleukin-10/19/20/22/24/26 family
Interleukin-10

About Release Notes Help Feedback

Logo License Policies Site Map

Contact: support@glycosmos.org

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements