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leucine rich repeat and fibronectin type III domain containing 3

Summary

Gene Symbol

Lrfn3

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

308495

PubChem

308495

Alliance of Genome Resources

RGD:1305567

Annotation

Keyword

Cell adhesion
Cell membrane
Cell projection
Disulfide bond
Glycoprotein
Immunoglobulin domain
Leucine-rich repeat
Postsynaptic cell membrane
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
B0BNK7	Synaptic adhesion-like molecule 4

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
regulation of synaptic membrane adhesion	IDA	27480238
regulation of synaptic membrane adhesion	IMP	27480238
synaptic membrane adhesion	IDA	18227064
synaptic membrane adhesion	IMP	18227064
regulation of presynapse assembly	IDA	27480238

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of synaptic membrane adhesion

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

regulation of presynapse organization [inference]

regulation of presynapse assembly

regulation of synaptic membrane adhesion

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of presynapse assembly

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GO Term	Evidence Code	PMID
cell surface	ISO
cell surface	IBA
axon	IEA
dendrite	IEA
presynaptic active zone membrane	IDA	18227064

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic active zone membrane

postsynaptic specialization membrane

postsynaptic density membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

leucine Rich Repeat

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

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InterPro
Cysteine-rich flanking region, C-terminal
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Leucine-rich repeat domain superfamily

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	79414	Xenbase:XB-GENE-923381	HUMAN42874
Mus musculus	233067	Xenbase:XB-GENE-923381	MOUSE54936
Xenopus tropicalis	308495	Xenbase:XB-GENE-923381
Pan troglodytes	468842		PANTR18056
Macaca mulatta	711565		MACMU18168
Bos taurus	767839		BOVIN10933
Equus caballus	100147099		HORSE01022
Callithrix jacchus	100393997		CALJA24803
Pongo abelii	100449370		PONAB14273
Ailuropoda melanoleuca	100472610		AILME11088