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torsin family 1, member B

Summary

Gene Symbol

Tor1b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

30934

PubChem

30934

Alliance of Genome Resources

MGI:1353605

Annotation

Keyword

ATP-binding
Chaperone
Endoplasmic reticulum
Glycoprotein
Hydrolase
Membrane
Nucleus
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9ER41	Torsin ATPase-1B Torsin family 1 member B

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
endoplasmic reticulum organization	ISS
endoplasmic reticulum organization	ISO
protein localization to nucleus	IBA
chaperone cofactor-dependent protein refolding	IEA
nuclear membrane organization	IGI	20457914

GO Hierarchy

biological process

cellular process [inference]

protein folding [inference]

'de novo' protein folding [inference]

'de novo' post-translational protein folding [inference]

chaperone cofactor-dependent protein refolding

chaperone-mediated protein folding [inference]

chaperone cofactor-dependent protein refolding

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

endoplasmic reticulum organization

membrane organization [inference]

nuclear membrane organization

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus

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GO Term	Evidence Code	PMID
nuclear envelope	ISO
nuclear envelope	IDA	20457914
nuclear envelope	IBA
cytoplasm	IDA	11730696
endoplasmic reticulum	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane [inference]

organelle membrane [inference]

nuclear membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	20457914
ATP binding	IEA
ATP hydrolysis activity	ISS
ATP hydrolysis activity	ISO
kinesin binding	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

kinesin binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Torsin

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
ATP binding

Displaying **all 4** entries
InterPro
ClpA/B family
P-loop containing nucleoside triphosphate hydrolase
Torsin-1A, C-terminal domain
Torsin

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	1861	ZFIN:ZDB-GENE-080917-50
Homo sapiens	27348	Xenbase:XB-GENE-986914	HUMAN98863
Drosophila melanogaster	27433	FB:FBgn0025615
Danio rerio	30931	ZFIN:ZDB-GENE-080917-50
Drosophila melanogaster	30933	FB:FBgn0025615
Xenopus tropicalis	30934	Xenbase:XB-GENE-986914
Drosophila melanogaster	30935	FB:FBgn0025615
Xenopus tropicalis	31399	Xenbase:XB-GENE-986914
Drosophila melanogaster	64222	FB:FBgn0025615
Xenopus tropicalis	174433	Xenbase:XB-GENE-986914

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Acknowledgements