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frizzled 3

Summary

Gene Symbol

fz3

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

31023

PubChem

31023

Alliance of Genome Resources

FB:FBgn0027343

Annotation

Keyword

Developmental protein
Disulfide bond
G-protein coupled receptor
Glycoprotein
RNA-binding
Reference proteome
Signal
Transmembrane helix
Wnt signaling pathway

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A8JUT5
X2JC46
O77438

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell surface receptor signaling pathway	IEA
canonical Wnt signaling pathway	IBA
establishment or maintenance of cell polarity	IMP	10498678
non-canonical Wnt signaling pathway	IBA

GO Hierarchy

biological process

cellular process [inference]

establishment or maintenance of cell polarity

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway [inference]

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

Wnt signaling pathway [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA ISS NAS	10498678 10908591
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Wnt-protein binding	IBA IPI	12205098
RNA binding	IEA
G protein-coupled receptor activity
Wnt receptor activity	IBA
transmembrane signaling receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

Wnt-protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

frizzled

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
Wnt receptor activity
Wnt-protein binding
canonical Wnt signaling pathway
cell surface receptor signaling pathway
non-canonical Wnt signaling pathway

Displaying **all 5** entries
InterPro
Frizzled cysteine-rich domain superfamily
Frizzled domain
Frizzled/Smoothened, 7TM
Frizzled/secreted frizzled-related protein
GPCR, family 2-like, 7TM

Ortholog

Displaying entries **21 - 30** of 45 in total

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Species	Gene ID	OrthoDB
Drosophila biarmipes	108024130	125945_1:0004d2
Drosophila rhopaloa	108046987	1041015_1:003273
Drosophila takahashii	108060120	29030_1:00358a
Drosophila kikkawai	108076076	30033_1:0015ac
Drosophila ficusphila	108097297	30025_1:000f70
Drosophila eugracilis	108105529	29029_0:001bc6
Drosophila bipectinata	108122836	42026_0:000b28
Drosophila elegans	108136324	30023_1:0005b1
Drosophila miranda	108164584	7229_0:002912
Drosophila busckii	108605256	30019_1:002a3e