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beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

Summary

Gene Symbol

B3galnt1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

310508

KEGG Gene ID

rno:310508

PubChem

310508

Alliance of Genome Resources

RGD:1304797

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid metabolism
Magnesium
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6J5N4
Q6AY39	Beta-1,3-galactosyltransferase 3 Beta-3-Gx-T3 Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase Globoside synthase UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein O-linked glycosylation	IBA
lipid metabolic process	IEA
oligosaccharide biosynthetic process	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

biosynthetic process [inference]

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide biosynthetic process

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

lipid metabolic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance biosynthetic process [inference]

carbohydrate biosynthetic process [inference]

oligosaccharide biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
Golgi membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	ISO
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	IBA
galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity

UDP-galactosyltransferase activity [inference]

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

hexosyltransferase activity [inference]

acetylgalactosaminyltransferase activity [inference]

galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity

galactosyltransferase activity [inference]

UDP-galactosyltransferase activity [inference]

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

beta-1,3-galactosyltransferase activity [inference]

UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

beta-1

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
UDP-galactose
hexosyltransferase activity
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase, family 31

KEGG BRITE Database

Orthology

K00719

Name

galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79]

References

10993897

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R11321	2.4.1.79	G78074HX	G57710SU
R11378	2.4.1.79	G58896AZ	G32252UW
R05962	2.4.1.79	G00059MO	G00061MO

Rhea

RHEA:22252

a globoside Gb3Cer (d18:1(4E)) + UDP-N-acetyl-α-D-galactosamine

H⁺ + a globoside Gb4Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.79

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013325
Gene Name: beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)

Ortholog

Displaying entries **1 - 10** of 98 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	8705	WB:WBGene00000270
Homo sapiens	8706	HGNC:918	HUMAN73198
Drosophila melanogaster	8707	FB:FBgn0031986
Caenorhabditis elegans	8708	WB:WBGene00000270
Drosophila melanogaster	10317	FB:FBgn0031986
Drosophila melanogaster	10331	FB:FBgn0000221
Drosophila melanogaster	10678	FB:FBgn0000221
Drosophila melanogaster	26877	FB:FBgn0031986
Drosophila melanogaster	26878	FB:FBgn0031986
Mus musculus	26879	HGNC:918	MOUSE36486

GlyTouCan

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UniCarb-DR

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements