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Guidelines

MIRAGE

mannosidase beta

Summary

Gene Symbol

Manba

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

310864

PubChem

310864

Alliance of Genome Resources

RGD:1305785

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycoprotein
Glycosidase
Lysosome
Reference proteome
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q4FZV0	Lysosomal beta A mannosidase Mannanase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
glycoprotein catabolic process	ISS
glycoprotein catabolic process	ISO
glycoprotein catabolic process	IBA
oligosaccharide catabolic process	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

oligosaccharide metabolic process [inference]

oligosaccharide catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

glycoprotein catabolic process

protein catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

carbohydrate catabolic process [inference]

oligosaccharide catabolic process

carbohydrate derivative catabolic process [inference]

glycoprotein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

glycoprotein catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	ISO
lysosomal lumen	ISO
intracellular membrane-bounded organelle	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle

intracellular organelle [inference]

intracellular membrane-bounded organelle

Displaying **all 5** entries
GO Term	Evidence Code	PMID
beta-mannosidase activity	ISO
beta-mannosidase activity	IDA	8702598
beta-mannosidase activity	IBA
mannose binding	IDA	8702598
hydrolase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

mannosidase activity [inference]

beta-mannosidase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

mannose binding

small molecule binding [inference]

monosaccharide binding [inference]

mannose binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

beta-mannosidase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism

Displaying **all 4** entries
Gene Ontology
beta-mannosidase activity
glycoprotein catabolic process
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 7** entries
InterPro
Beta-Galactosidase/glucuronidase domain superfamily
Beta-mannosidase, Ig-fold domain
Galactose-binding-like domain superfamily
Glycoside hydrolase family 2, catalytic domain
Glycoside hydrolase superfamily
Immunoglobulin-like fold
Mannosidase Ig/CBM-like domain

Ortholog

Displaying entries **1 - 10** of 76 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	4126	Xenbase:XB-GENE-985698	HUMAN76775
Mus musculus	110173	Xenbase:XB-GENE-985698	MOUSE37946
Xenopus tropicalis	181517	Xenbase:XB-GENE-985698
Bos taurus	281909		BOVIN31131
Xenopus tropicalis	310864	Xenbase:XB-GENE-985698
Pan troglodytes	461407		PANTR34213
Canis lupus familiaris	487883		CANLF13115
Macaca mulatta	712531		MACMU37522
Monodelphis domestica	100014402		MONDO26482
Pongo abelii	100171985		PONAB27286

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025