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Guidelines

MIRAGE

annexin A7

Summary

Gene Symbol

ANXA7

Organism

Homo sapiens (human)

External Links

NCBI Gene

310

HGNC

545

KEGG Gene ID

hsa:310

PubChem

310

Alliance of Genome Resources

HGNC:545

Annotation

Keyword

Acetylation
Alternative splicing
Annexin
Calcium/phospholipid-binding
Direct protein sequencing
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P20073	Annexin VII Annexin-7 Synexin
B2R657

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
autophagy	IMP	24007983
negative regulation of gene expression	IMP	24007983
epithelial cell differentiation	IEP	21492153

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

autophagy

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

process utilizing autophagic mechanism [inference]

autophagy

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

epithelial cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

negative regulation of gene expression

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nucleus	IDA	10672515
nucleus	IBA
cytoplasm	IBA
endoplasmic reticulum membrane	IDA	10672515
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

plasma membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane

cytoplasmic vesicle membrane [inference]

secretory granule membrane [inference]

chromaffin granule membrane

bounding membrane of organelle [inference]

secretory granule membrane [inference]

chromaffin granule membrane

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
phosphatidylserine binding	IBA
RNA binding	HDA	22681889
integrin binding	IPI	24007983
calcium ion binding	IEA
protein binding	IPI	12445460 17699613 9268363

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

calcium-dependent protein binding

cell adhesion molecule binding [inference]

integrin binding

lipid binding [inference]

phospholipid binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

calcium ion binding

protein-containing complex binding [inference]

integrin binding

modified amino acid binding [inference]

phosphatidylserine binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

annexin I

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
N: Cell motility
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
calcium ion binding
calcium-dependent phospholipid binding

Displaying **all 4** entries
InterPro
Annexin repeat, conserved site
Annexin repeat
Annexin superfamily
Annexin

KEGG BRITE Database

Orthology

K17095

Name

annexin A7/11

References

Ortholog

Displaying entries **11 - 20** of 75 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Equus caballus	100072856		HORSE18051
Ornithorhynchus anatinus	100073854		ORNAN17693
Sus scrofa	100156638		PIGXX07818
Ciona intestinalis	100182180		CIOIN11114
Taeniopygia guttata	100222273		TAEGU27308
Oryctolagus cuniculus	100338267		RABIT06697
Callithrix jacchus	100388250		CALJA07473
Callithrix jacchus	100388851		CALJA07473
Pongo abelii	100438043		PONAB01199
Ailuropoda melanoleuca	100479169		AILME11602

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025