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Submissions

shaggy

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

31248

PubChem

31248

Alliance of Genome Resources

FB:FBgn0003371

Annotation

Keyword

ATP-binding
Alternative splicing
Cell projection
Cytoskeleton
Meiosis
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Segmentation polarity protein
Serine/threonine-protein kinase
Synapse

Proteins

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UniProt	Protein Name
Q7KVY5
A8JUV9
B6IDN4
A4V3W2
M9PGC4
M9PGV7
H5V852
Q0KHW6
C0PUX5
A4V3W1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 40 in total

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GO Term	Evidence Code	PMID
synaptic assembly at neuromuscular junction	IMP	15269269
establishment of epithelial cell planar polarity	IGI IMP	21483653
positive regulation of mitotic metaphase/anaphase transition	IMP	19029800
chitin-based larval cuticle pattern formation	IMP	19737741 9630748
pseudocleavage involved in syncytial blastoderm formation	NAS	16570248

GO Hierarchy

biological process

metabolic process [inference]

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

glucan metabolic process [inference]

glycogen metabolic process

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization

establishment or maintenance of cell polarity [inference]

establishment of cell polarity [inference]

establishment of epithelial cell polarity [inference]

establishment of epithelial cell planar polarity

signal transduction

cell cycle process [inference]

spindle organization

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

female meiotic nuclear division

cellular process involved in reproduction in multicellular organism [inference]

female meiotic nuclear division

germ cell development [inference]

oogenesis

follicle cell of egg chamber development

cellular metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

cellular developmental process [inference]

cell differentiation

cell development [inference]

epithelial cell development [inference]

follicle cell of egg chamber development

germ cell development [inference]

oogenesis

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division [inference]

female meiotic nuclear division

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

synapse organization [inference]

synapse assembly [inference]

synaptic assembly at neuromuscular junction

neuromuscular junction development [inference]

synaptic assembly at neuromuscular junction

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

follicle cell of egg chamber development

cellular process involved in reproduction in multicellular organism [inference]

female meiotic nuclear division

germ cell development [inference]

oogenesis

follicle cell of egg chamber development

multicellular organismal reproductive process [inference]

gamete generation [inference]

female gamete generation [inference]

oogenesis

meiotic cell cycle process [inference]

meiotic nuclear division [inference]

female meiotic nuclear division

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

olfactory learning

nonassociative learning [inference]

habituation

pattern specification process [inference]

regionalization [inference]

periodic partitioning [inference]

segment polarity determination

cuticle pattern formation [inference]

chitin-based larval cuticle pattern formation

wing and notum subfield formation

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

olfactory learning

nonassociative learning [inference]

habituation

rhythmic behavior

circadian behavior [inference]

locomotor rhythm

locomotory behavior [inference]

locomotor rhythm

chemosensory behavior [inference]

olfactory behavior [inference]

olfactory learning

stem cell population maintenance [inference]

somatic stem cell population maintenance

pseudocleavage [inference]

pseudocleavage involved in syncytial blastoderm formation

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development [inference]

oogenesis

follicle cell of egg chamber development

anatomical structure morphogenesis [inference]

cell morphogenesis [inference]

epithelial cell morphogenesis

post-embryonic animal morphogenesis [inference]

imaginal disc-derived wing margin morphogenesis

animal organ morphogenesis [inference]

chaeta morphogenesis

anatomical structure development [inference]

cell development [inference]

epithelial cell development [inference]

follicle cell of egg chamber development

germ cell development [inference]

oogenesis

animal organ development [inference]

sensory organ development [inference]

chaeta development

heart development

cellular developmental process [inference]

cell differentiation

cell development [inference]

epithelial cell development [inference]

follicle cell of egg chamber development

germ cell development [inference]

oogenesis

maintenance of cell number [inference]

stem cell population maintenance [inference]

somatic stem cell population maintenance

growth [inference]

developmental growth [inference]

synaptic assembly at neuromuscular junction

rhythmic process [inference]

circadian rhythm

circadian behavior [inference]

locomotor rhythm

response to stimulus [inference]

response to external stimulus [inference]

entrainment of circadian clock

response to chemical [inference]

response to anesthetic

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of nitrogen compound metabolic process [inference]

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein metabolic process [inference]

regulation of proteolysis

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of proteolysis

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteolysis involved in protein catabolic process [inference]

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of ubiquitin-dependent protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of proteasomal protein catabolic process [inference]

regulation of proteasomal ubiquitin-dependent protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

regulation of calcineurin-mediated signaling [inference]

regulation of calcineurin-NFAT signaling cascade

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of localization [inference]

regulation of transport [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus

regulation of growth [inference]

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of circadian rhythm

entrainment of circadian clock

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process [inference]

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of proteolysis [inference]

positive regulation of proteolysis involved in protein catabolic process

positive regulation of proteasomal protein catabolic process [inference]

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of ubiquitin-dependent protein catabolic process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of chromosome separation [inference]

positive regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of growth [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

regulation of calcineurin-mediated signaling [inference]

regulation of calcineurin-NFAT signaling cascade

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to insulin stimulus [inference]

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of developmental process [inference]

regulation of developmental growth [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of developmental process [inference]

negative regulation of developmental growth [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of cellular process [inference]

signal transduction

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway [inference]

negative regulation of smoothened signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of insulin receptor signaling pathway [inference]

negative regulation of insulin receptor signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of BMP signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of intracellular signal transduction [inference]

regulation of calcium-mediated signaling [inference]

regulation of calcineurin-mediated signaling [inference]

regulation of calcineurin-NFAT signaling cascade

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of microtubule-based process [inference]

regulation of microtubule cytoskeleton organization

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of chromosome separation [inference]

positive regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of chromosome organization [inference]

regulation of sister chromatid segregation [inference]

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of cytoskeleton organization [inference]

regulation of microtubule cytoskeleton organization

regulation of nuclear division [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of neuromuscular junction development [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse organization [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of neuromuscular junction development [inference]

negative regulation of synaptic assembly at neuromuscular junction

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

regulation of synaptic assembly at neuromuscular junction [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of cell cycle process [inference]

regulation of mitotic nuclear division [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of chromosome segregation [inference]

regulation of sister chromatid segregation [inference]

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of chromosome separation [inference]

positive regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of chromosome separation [inference]

positive regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of cell cycle phase transition [inference]

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of mitotic cell cycle phase transition [inference]

regulation of mitotic metaphase/anaphase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle process [inference]

positive regulation of mitotic nuclear division [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of metaphase/anaphase transition of cell cycle [inference]

positive regulation of mitotic metaphase/anaphase transition

positive regulation of chromosome separation [inference]

positive regulation of mitotic sister chromatid separation [inference]

positive regulation of mitotic metaphase/anaphase transition

regulation of cellular localization [inference]

regulation of intracellular transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of nucleocytoplasmic transport [inference]

regulation of protein import into nucleus

regulation of protein localization [inference]

regulation of establishment of protein localization [inference]

regulation of protein transport [inference]

regulation of intracellular protein transport [inference]

regulation of protein import into nucleus

regulation of protein localization to nucleus [inference]

regulation of protein import into nucleus

regulation of cellular response to insulin stimulus [inference]

negative regulation of cellular response to insulin stimulus [inference]

negative regulation of insulin receptor signaling pathway

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly [inference]

negative regulation of synaptic assembly at neuromuscular junction

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GO Term	Evidence Code	PMID
cell cortex
fusome	IDA	18355804
beta-catenin destruction complex	IDA	31189665
plasma membrane
neuromuscular junction	IDA	15269269

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

beta-catenin destruction complex

catalytic complex [inference]

beta-catenin destruction complex

cellular anatomical entity [inference]

nucleoplasm

cytoplasm

cell cortex

microtubule organizing center [inference]

centrosome

cytosol

membrane [inference]

plasma membrane

cell junction [inference]

synapse [inference]

neuromuscular junction

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

spindle [inference]

mitotic spindle

fusome

intercellular bridge [inference]

germline ring canal [inference]

female germline ring canal

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IPI	15691767 19850033
protein serine kinase activity
protein serine/threonine kinase activity	IBA IDA IMP	11912487 11927557 11955435 14966281 16222340 19364825 21628596 25377173 29408853 7529201
ATP binding	IEA
protein kinase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kinase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 7** entries
Gene Ontology
ATP binding
kinase activity
nucleotide binding
phosphorylation
protein serine/threonine/tyrosine kinase activity
regulation of neuron projection development
transferase activity

Displaying **all 5** entries
InterPro
Glycogen synthase kinase 3, catalytic domain
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine/threonine-protein kinase, active site

Alliance of Genome Resources

Expression

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Location	References
fusome	PMID:18355804
membrane	FB:FBrf0231198
nucleus	PMID:15691767 PMID:16570248 PMID:19029800
beta-catenin destruction complex	PMID:31189665
nucleoplasm	PMID:19029800
centrosome	PMID:16570248 PMID:19029800 PMID:25294944
axon	PMID:15269269
cytosol	PMID:25294944 PMID:31189665
spectrosome	PMID:18355804
cytoplasm	PMID:15691767 PMID:19029800

Disease

Disease Ontology

Displaying entries **1 - 10** of 23 in total

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DO ID	Disease Name	Source
DOID:0050850	diabetic encephalopathy	Alliance of Genome Resources
DOID:0050861	colorectal adenocarcinoma	Alliance of Genome Resources
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources
DOID:0080855	Parkinsonism	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:114	heart disease	Alliance of Genome Resources
DOID:11446	sciatic neuropathy	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources
DOID:1596	depressive disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 50 in total

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Species	Gene ID	Alliance of Genome Resources
Homo sapiens	2931	HGNC:4616
Homo sapiens	2932	HGNC:4617
Danio rerio	30654	ZFIN:ZDB-GENE-990714-4
Danio rerio	30664	ZFIN:ZDB-GENE-990714-3
Rattus norvegicus	50686	RGD:620351
Mus musculus	56637	MGI:1861437
Rattus norvegicus	84027	RGD:70982
Caenorhabditis elegans	173149	WB:WBGene00001746
Danio rerio	557882	ZFIN:ZDB-GENE-090312-2
Danio rerio	560194	ZFIN:ZDB-GENE-060503-796

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements