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mannose-6-phosphate receptor, cation dependent

Summary

Gene Symbol

M6pr

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

312689

PubChem

312689

Alliance of Genome Resources

RGD:1359355

Annotation

Keyword

Disulfide bond
Glycoprotein
Lysosome
Phosphoprotein
Receptor
Reference proteome
Signal
Transmembrane helix
Transport

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6ILE1
Q6AY20

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein targeting to lysosome	IBA IEA
secretion of lysosomal enzymes	ISO
lysosomal transport	ISO ISS

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

secretion of lysosomal enzymes

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion [inference]

secretion of lysosomal enzymes

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

organic substance transport [inference]

protein transport [inference]

protein secretion [inference]

secretion of lysosomal enzymes

nitrogen compound transport [inference]

protein transport [inference]

protein secretion [inference]

secretion of lysosomal enzymes

export from cell [inference]

secretion by cell [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of localization in cell [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

cellular localization [inference]

intracellular transport [inference]

vacuolar transport [inference]

lysosomal transport

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to vacuole [inference]

protein localization to lysosome [inference]

protein targeting to lysosome

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein transport [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole [inference]

protein targeting to lysosome

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion [inference]

secretion of lysosomal enzymes

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
membrane	IEA
Golgi apparatus	IEA
late endosome	ISO
endosome	IEA ISO
trans-Golgi network	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

organelle subcompartment [inference]

Golgi apparatus subcompartment [inference]

trans-Golgi network

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

late endosome

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

late endosome

perinuclear region of cytoplasm

Displaying **all 2** entries
GO Term	Evidence Code	PMID
retromer complex binding	ISO
protein domain specific binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

protein domain specific binding

protein-containing complex binding [inference]

retromer complex binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Cation-dependent mannose-6-phosphate receptor

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
N: Cell motility

Displaying **all 2** entries
Gene Ontology
protein domain specific binding
protein targeting to lysosome

Displaying **all 4** entries
InterPro
Cation-dependent mannose-6-phosphate receptor
MRH domain
Mannose-6-phosphate receptor binding domain superfamily
Mannose-6-phosphate receptor

Ortholog

Displaying entries **1 - 10** of **109** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	4074		HGNC:6752	HUMAN11060
Mus musculus	17113	10090_1:001c6a	MGI:96904	MOUSE47430
Bos taurus	281291			BOVIN30326
Danio rerio	406486		ZFIN:ZDB-GENE-040426-2285	DANRE10575
Xenopus tropicalis	493477		Xenbase:XB-GENE-991688
Takifugu rubripes	654276			TAKRU45859
Macaca mulatta	716696			MACMU04704
Pan troglodytes	736013			PANTR05101
Monodelphis domestica	100012242			MONDO33661
Sus scrofa	100154117			PIGXX26225

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024