GlyCosmos Portal

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
transcription coactivator binding	IPI	27956576
protein serine/threonine kinase activity	ISO
JUN kinase kinase kinase activity	IEA
MAP kinase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein serine/threonine kinase activity

MAP kinase activity

MAP kinase kinase kinase activity

JUN kinase kinase kinase activity

MAP kinase kinase kinase kinase activity

protein serine/threonine/tyrosine kinase activity [inference]

MAP kinase kinase activity

histone modifying activity [inference]

histone kinase activity

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding [inference]

transforming growth factor beta receptor binding [inference]

type II transforming growth factor beta receptor binding

receptor tyrosine kinase binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription coactivator binding

DNA-binding transcription factor binding

enzyme binding

kinase binding [inference]

protein kinase binding [inference]

protein serine/threonine kinase binding

protein tyrosine kinase binding [inference]

receptor tyrosine kinase binding

ubiquitin-like protein ligase binding [inference]

ubiquitin protein ligase binding

ubiquitin-like protein binding [inference]

ubiquitin binding [inference]

linear polyubiquitin binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding [inference]

magnesium ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

mitogen-activated protein kinase

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 9** entries
Gene Ontology
ATP binding
JNK cascade
immune response
kinase activity
magnesium ion binding
nucleotide binding
phosphorylation
positive regulation of canonical NF-kappaB signal transduction
transferase activity

Displaying **all 7** entries
InterPro
Mitogen-activated protein (MAP) kinase kinase kinase 7-like
Mitogen-activated protein kinase kinase kinase 7
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Serine/threonine-protein kinase, active site

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2349	arteriosclerosis	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6885	Xenbase:XB-GENE-481530	HUMAN85792
Mus musculus	26409	Xenbase:XB-GENE-481530	MOUSE42368
Xenopus tropicalis	313121	Xenbase:XB-GENE-481530
Pan troglodytes	462888		PANTR38711
Bos taurus	529146		BOVIN35676
Danio rerio	553788		DANRE18992
Macaca mulatta	703101		MACMU33403
Monodelphis domestica	100019975		MONDO12228
Equus caballus	100065841		HORSE01106
Sus scrofa	100135663		PIGXX13693

GlyTouCan

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OrthoDB (Group)

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Acknowledgements