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alpha-N-acetylgalactosaminidase

Summary

Gene Symbol

Naga

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

315165

PubChem

315165

Alliance of Genome Resources

RGD:1306025

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lipid metabolism
Lysosome
Phosphoprotein
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HT60
Q66H12	Alpha-galactosidase B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycolipid catabolic process	IEA ISO ISS
carbohydrate catabolic process	IEA ISO ISS
biological_process	ND
glycoside catabolic process	IBA
oligosaccharide metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

carbohydrate catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

glycoside catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

carbohydrate catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysosome	IEA
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
hydrolase activity, hydrolyzing O-glycosyl compounds	IEA
alpha-N-acetylgalactosaminidase activity	IEA ISO ISS
alpha-galactosidase activity	IBA
protein homodimerization activity	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds

galactosidase activity [inference]

alpha-galactosidase activity

hexosaminidase activity [inference]

alpha-N-acetylgalactosaminidase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-N-acetylgalactosaminidase

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
alpha-galactosidase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lipid metabolic process

Displaying **all 6** entries
InterPro
Aldolase-type TIM barrel
Alpha galactosidase A, C-terminal beta-sandwich domain
Glycoside hydrolase family 27/36, conserved site
Glycoside hydrolase superfamily
Glycoside hydrolase, family 27
Glycosyl hydrolase, all-beta

Rhea

RHEA:15085

an N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl derivative + H₂O

an α-L-fucosyl-(1→2)-β-D-galactosyl derivative + N-acetyl-D-galactosamine

Enzyme

3.2.1.49

PMID

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0112318	Schindler disease type 1	Alliance of Genome Resources
DOID:0112319	Kanzaki disease	Alliance of Genome Resources
DOID:14499	Fabry disease	Alliance of Genome Resources
DOID:2367	neuroaxonal dystrophy	Alliance of Genome Resources
DOID:479	angiokeratoma	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013382
Gene Name: N-acetyl galactosaminidase, alpha

Ortholog

Displaying entries **111 - 120** of **124** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Panthera leo	122225203		PANLE18007
Marmota monax	124082862	9995_0:004378
Sciurus carolinensis	124982310	30640_0:001941
Perognathus longimembris pacificus	125357570	214514_0:00036b
Myodes glareolus	125407445	447135_0:001ed4
Microtus fortis	126515716	100897_0:00397b
Acomys russatus	127201471	60746_0:002c90
Phodopus roborovskii	127225858	109678_0:0025bc
Apodemus sylvaticus	127668213	10129_0:004420
Peromyscus californicus insignis	128116836	564181_0:001de5

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements