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alpha-N-acetylgalactosaminidase

Summary

Gene Symbol

Naga

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

315165

PubChem

315165

Alliance of Genome Resources

RGD:1306025

Annotation

Keyword

Disulfide bond
Glycoprotein
Glycosidase
Lipid metabolism
Lysosome
Phosphoprotein
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HT60
Q66H12	Alpha-galactosidase B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
glycolipid catabolic process	IEA ISO ISS
carbohydrate catabolic process	IEA ISO ISS
biological_process	ND
glycoside catabolic process	IBA
oligosaccharide metabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

carbohydrate catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

glycoside catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

carbohydrate catabolic process

carbohydrate derivative catabolic process [inference]

glycolipid catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular catabolic process [inference]

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycolipid catabolic process

membrane lipid catabolic process [inference]

glycolipid catabolic process

cellular lipid catabolic process [inference]

membrane lipid catabolic process [inference]

glycolipid catabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
lysosome	IEA
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 4** entries
GO Term	Evidence Code	PMID
hydrolase activity, hydrolyzing O-glycosyl compounds	IEA
alpha-N-acetylgalactosaminidase activity	IEA ISO ISS
alpha-galactosidase activity	IBA
protein homodimerization activity	IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds

galactosidase activity [inference]

alpha-galactosidase activity

hexosaminidase activity [inference]

alpha-N-acetylgalactosaminidase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-N-acetylgalactosaminidase

Functional Category

D: Cell cycle control, cell division, chromosome partitioning
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
alpha-galactosidase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity
lipid metabolic process

Displaying **all 6** entries
InterPro
Aldolase-type TIM barrel
Alpha galactosidase A, C-terminal beta-sandwich domain
Glycoside hydrolase family 27/36, conserved site
Glycoside hydrolase superfamily
Glycoside hydrolase, family 27
Glycosyl hydrolase, all-beta

Rhea

RHEA:15085

an N-acetyl-α-D-galactosaminyl-(1→3)-[α-L-fucosyl-(1→2)]-β-D-galactosyl derivative + H₂O

an α-L-fucosyl-(1→2)-β-D-galactosyl derivative + N-acetyl-D-galactosamine

Enzyme

3.2.1.49

PMID

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0112318	Schindler disease type 1	Alliance of Genome Resources
DOID:0112319	Kanzaki disease	Alliance of Genome Resources
DOID:14499	Fabry disease	Alliance of Genome Resources
DOID:2367	neuroaxonal dystrophy	Alliance of Genome Resources
DOID:479	angiokeratoma	Alliance of Genome Resources

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP013382
Gene Name: N-acetyl galactosaminidase, alpha

Ortholog

Displaying entries **11 - 20** of **124** in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	779501	Xenbase:XB-GENE-5832581
Monodelphis domestica	100018362		MONDO35294
Ornithorhynchus anatinus	100086854		ORNAN06438
Sus scrofa	100142667		PIGXX24976
Ovis aries	100145858		SHEEP15162
Ciona intestinalis	100182270		CIOIN12149
Salmo salar	100195244		SALSA38301
Oryctolagus cuniculus	100350048		RABIT15059
Callithrix jacchus	100397642		CALJA20304
Pongo abelii	100450338		PONAB22216

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements