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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
junctional adhesion molecule 3
Summary
- Gene Symbol
-
- Jam3
- Organism
- Rattus norvegicus (Norway rat)
Annotation
- Keyword
-
- Cell adhesion
- Cell membrane
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Palmitate
- Reference proteome
- Secreted
- Signal
- Spermatogenesis
- Tight junction
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of integrin activation | ||
| hematopoietic stem cell migration to bone marrow | ||
| axon regeneration | ||
| establishment of cell polarity | ||
| angiogenesis |
GO Hierarchy
biological process
cellular process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cell-cell contact zone | ||
| plasma membrane | ||
| Schmidt-Lanterman incisure | ||
| tight junction | ||
| cell-cell junction |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| integrin binding | ||
| protein heterodimerization activity | ||
| identical protein binding | ||
| protein homodimerization activity | ||
| cell-cell adhesion mediator activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- Junctional adhesion molecule C
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell migration |
| cell-cell adhesion mediator activity |
| integrin binding |
| protein heterodimerization activity |
| protein homodimerization activity |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:11446 | sciatic neuropathy | |
| DOID:418 | systemic scleroderma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 105980891 | 10020_0:000a3e | |||
| 107153555 | 9994_0:004d5a | |||
| 107548190 | SINGR17435 | |||
| 107561060 | SINGR75636 | |||
| 108279240 | ICTPU11700 | |||
| 108529694 | RHIBE08734 | |||
| 109698805 | 51338_0:003cba | |||
| 110195824 | PHACI03912 | |||
| 110301490 | 10089_0:002b2a | |||
| 110327722 | 10093_0:002bb5 |
