GlyCosmos Portal

Annotation

Keyword

3D-structure
Acetylation
Cholesterol biosynthesis
Cytoplasm
Phosphoprotein
Reference proteome
Transferase

Proteins

Displaying 1 entry
UniProt	Protein Name
Q01581	3-hydroxy-3-methylglutaryl coenzyme A synthase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cholesterol biosynthetic process
lipid metabolic process		7913309
acetyl-CoA metabolic process	IBA
farnesyl diphosphate biosynthetic process, mevalonate pathway	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

amide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

lipid metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic substance metabolic process [inference]

lipid metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organonitrogen compound metabolic process [inference]

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

secondary alcohol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

sterol metabolic process [inference]

cholesterol metabolic process [inference]

cholesterol biosynthetic process

sterol biosynthetic process [inference]

cholesterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

cholesterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

cholesterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

sulfur compound metabolic process [inference]

thioester metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

organophosphate biosynthetic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

cellular biosynthetic process [inference]

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

cellular lipid metabolic process [inference]

phospholipid metabolic process [inference]

phospholipid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

farnesyl diphosphate metabolic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process [inference]

terpenoid biosynthetic process [inference]

farnesyl diphosphate biosynthetic process [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

isoprenoid biosynthetic process via mevalonate [inference]

farnesyl diphosphate biosynthetic process, mevalonate pathway

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

ribonucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

nucleoside bisphosphate metabolic process [inference]

ribonucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine-containing compound metabolic process [inference]

purine nucleotide metabolic process [inference]

purine ribonucleotide metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

purine nucleoside bisphosphate metabolic process [inference]

acyl-CoA metabolic process [inference]

acetyl-CoA metabolic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
cytosol
cytoplasm		7913309

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein homodimerization activity	IDA	20346956
hydroxymethylglutaryl-CoA synthase activity	IBA TAS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, acyl groups converted into alkyl on transfer [inference]

hydroxymethylglutaryl-CoA synthase activity

binding [inference]

protein binding [inference]

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000112972

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K01641

Name

hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]

References

8566777

Rhea

RHEA:10188

H₂O + acetoacetyl-CoA + acetyl-CoA

H⁺ + (3S)-hydroxy-3-methylglutaryl-CoA + CoA

Enzyme

2.3.3.10

PMID

Disease

Disease Ontology

Displaying entries **1 - 10** of 12 in total

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DO ID	Disease Name	Source
DOID:10283	prostate cancer	DisGeNET
DOID:10286	prostate carcinoma	DisGeNET
DOID:1520	colon carcinoma	DisGeNET
DOID:1883	hepatitis C	DisGeNET
DOID:219	colon cancer	DisGeNET
DOID:235	colonic benign neoplasm	DisGeNET
DOID:319	spinal cord disease	DisGeNET
DOID:5672	large intestine cancer	DisGeNET
DOID:684	hepatocellular carcinoma	DisGeNET
DOID:687	hepatoblastoma	DisGeNET

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP001950
Gene Name: 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

Ortholog

Displaying entries **1 - 10** of 91 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	178956	WB:WBGene00017769
Drosophila melanogaster	44154	FB:FBgn0010611
Ciona intestinalis	100175295		CIOIN08080
Danio rerio	394060	ZFIN:ZDB-GENE-040426-1042	DANRE00551
Astyanax mexicanus	103042817		ASTMX10566
Ictalurus punctatus	108277226		ICTPU08778
Electrophorus electricus	113576734		ELEEL20153
Salmo trutta	115160091		SALTR69759
Gadus morhua	115542156		GADMO46427
Oryzias latipes	101172510		ORYLA02882

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements