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ADAM metallopeptidase with thrombospondin type 1 motif, 7

Summary

Gene Symbol

Adamts7

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

315879

PubChem

315879

Alliance of Genome Resources

RGD:1306713

Annotation

Keyword

Alternative splicing
Calcium
Cleavage on pair of basic residues
Disulfide bond
Extracellular matrix
Glycoprotein
Metal-binding
Metalloprotease
Proteoglycan
Reference proteome
Repeat
Signal
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A140TAF3
Q1EHB3	COMPase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

1

2

3

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Last »
GO Term	Evidence Code	PMID
proteolysis	IBA IEA ISO
ossification involved in bone maturation	ISO
cellular response to interleukin-1	ISO
proteoglycan metabolic process	ISO
chondrocyte differentiation	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

proteolysis involved in protein catabolic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

proteolysis involved in protein catabolic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

proteolysis involved in protein catabolic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process

carbohydrate derivative metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

proteolysis involved in protein catabolic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

collagen fibril organization

external encapsulating structure organization [inference]

extracellular matrix organization

collagen fibril organization

supramolecular fiber organization [inference]

collagen fibril organization

multicellular organismal process [inference]

ossification

ossification involved in bone maturation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

response to stimulus [inference]

response to endogenous stimulus [inference]

response to growth factor [inference]

cellular response to growth factor stimulus [inference]

cellular response to BMP stimulus

response to BMP [inference]

cellular response to BMP stimulus

cellular response to endogenous stimulus [inference]

cellular response to growth factor stimulus [inference]

cellular response to BMP stimulus

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to tumor necrosis factor [inference]

cellular response to tumor necrosis factor

response to interleukin-1 [inference]

cellular response to interleukin-1

cellular response to cytokine stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

regulation of developmental process [inference]

regulation of cell differentiation [inference]

regulation of chondrocyte differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cell differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

regulation of multicellular organismal development [inference]

regulation of cartilage development [inference]

regulation of chondrocyte differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

regulation of cellular process [inference]

regulation of cell differentiation [inference]

regulation of chondrocyte differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cell differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cellular process [inference]

negative regulation of cell differentiation [inference]

negative regulation of chondrocyte differentiation

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

regulation of multicellular organismal development [inference]

regulation of cartilage development [inference]

regulation of chondrocyte differentiation [inference]

negative regulation of chondrocyte differentiation

negative regulation of cartilage development [inference]

negative regulation of chondrocyte differentiation

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular matrix	IBA
extracellular region	IEA
cell surface	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

external encapsulating structure [inference]

extracellular matrix

Displaying **all 3** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
metallopeptidase activity	ISO
metalloendopeptidase activity	IBA IEA ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.1.1

Last updated: February 17, 2025

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