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solute carrier family 9 member A1

Summary

Gene Symbol

SLC9A1

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 317654
PubChem: 317654

Annotation

Keyword

Antiport
Calmodulin-binding
Cell membrane
Glycoprotein
Palmitate
Phosphoprotein
Reference proteome
Sodium transport
Transmembrane helix
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q28036	Na(+)/H(+) exchanger 1 Solute carrier family 9 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
regulation of pH	IEA	22301074
cellular response to acidic pH
sodium ion export across plasma membrane
proton transmembrane transport	IEA	22301074 30032202
protein complex oligomerization

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

monoatomic cation homeostasis [inference]

regulation of pH

regulation of cellular pH [inference]

regulation of intracellular pH

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH

response to stimulus [inference]

response to abiotic stimulus [inference]

response to pH [inference]

response to acidic pH

cellular response to acidic pH

cellular response to pH [inference]

cellular response to acidic pH

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to pH [inference]

cellular response to acidic pH

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

sodium ion transport

sodium ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

sodium ion transmembrane transport [inference]

potassium ion transmembrane transport

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

proton transmembrane transport

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

import across plasma membrane [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

export across plasma membrane [inference]

sodium ion export across plasma membrane

import into cell [inference]

inorganic ion import across plasma membrane [inference]

inorganic cation import across plasma membrane [inference]

sodium ion import across plasma membrane

export from cell [inference]

export across plasma membrane [inference]

sodium ion export across plasma membrane

biological regulation [inference]

regulation of pH

regulation of cellular pH [inference]

regulation of intracellular pH

regulation of biological quality [inference]

regulation of intracellular pH

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	IEA	22301074 30032202
plasma membrane
basolateral plasma membrane
cytoplasm

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytoplasm

membrane

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
calmodulin binding
potassium:proton antiporter activity
calcium-dependent protein binding
sodium:proton antiporter activity	IEA	22301074 30032202

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

proton transmembrane transporter activity [inference]

metal cation:proton antiporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

active monoatomic ion transmembrane transporter activity [inference]

metal cation:monoatomic cation antiporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

metal cation:proton antiporter activity [inference]

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

solute:potassium antiporter activity [inference]

potassium:proton antiporter activity

sodium ion transmembrane transporter activity [inference]

sodium:proton antiporter activity

binding [inference]

protein binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sodium/hydrogen exchanger

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
monoatomic ion transport
potassium
regulation of intracellular pH
regulation of pH
sodium ion transmembrane transport

Displaying **all 3** entries
InterPro
Cation/H+ exchanger, CPA1 family
Cation/H+ exchanger
Na+/H+ exchanger

Ortholog

Displaying entries **1 - 10** of **108** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Homo sapiens	6548		HUMAN48337
Mus musculus	20544		MOUSE40464
Rattus norvegicus	24782		RATNO32683
Sus scrofa	397458	9823_0:001fce	PIGXX29395
Pan troglodytes	456669		PANTR20368
Canis lupus familiaris	478171		CANLF06971
Ovis aries	494435	9940_0:000b56
Macaca mulatta	720079		MACMU25110
Equus caballus	100070959		HORSE27127
Ornithorhynchus anatinus	100088668		ORNAN07747