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Imaginal disc growth factor 4

Summary

Gene Symbol

Idgf4

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

31926

PubChem

31926

Alliance of Genome Resources

FB:FBgn0026415

Annotation

Keyword

Developmental protein
Disulfide bond
Glycoprotein
Glycosidase
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
X2JEB6
Q9W303	Imaginal disk growth factor protein 4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
wound healing	IMP	26838602
chitin catabolic process	IBA
chitin-based cuticle development	IMP	26838602
imaginal disc development	IDA	9847235
ecdysis, chitin-based cuticle	IMP	26838602

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

amino sugar metabolic process [inference]

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin catabolic process

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

multicellular organismal process [inference]

molting cycle process [inference]

ecdysis, chitin-based cuticle

developmental process [inference]

anatomical structure development [inference]

cuticle development [inference]

chitin-based cuticle development

animal organ development [inference]

imaginal disc development

response to stimulus [inference]

response to stress [inference]

response to wounding [inference]

wound healing

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	HDA IBA NAS	15466469 9847235

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chitin binding	IEA
imaginal disc growth factor receptor binding	IDA	9847235

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

growth factor receptor binding [inference]

imaginal disc growth factor receptor binding

carbohydrate derivative binding [inference]

chitin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chitinase A

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
chitin binding
chitin catabolic process
chitinase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 5** entries
InterPro
Chitinase II
Chitinase insertion domain superfamily
Glycoside hydrolase family 18, catalytic domain
Glycoside hydrolase superfamily
Glycosyl hydrolases family 18 (GH18) active site

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
cytoplasm	FB:FBrf0219073
extracellular region	PMID:15466469
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying entries **1 - 10** of 30 in total

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DO ID	Disease Name	Source
DOID:0050685	small cell carcinoma	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:10286	prostate carcinoma	Alliance of Genome Resources
DOID:10591	pre-eclampsia	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11650	bronchopulmonary dysplasia	Alliance of Genome Resources
DOID:13375	temporal arteritis	Alliance of Genome Resources
DOID:13406	pulmonary sarcoidosis	Alliance of Genome Resources
DOID:1380	endometrial cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of 51 in total

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Species	Gene ID	OrthoDB
Drosophila hydei	111603372	7224_1:001741
Drosophila novamexicana	115765270	47314_0:00222c
Drosophila mauritiana	117147647	7226_0:0034e0
Drosophila albomicans	117573665	7291_1:0000aa
Drosophila guanche	117580967	7266_1:0010fc
Drosophila innubila	117781756	198719_0:000605
Drosophila subobscura	117897170	7241_0:001db4
Drosophila subpulchrella	119556997	1486046_0:0004a9
Drosophila santomea	120456131	129105_1:00310f
Drosophila teissieri	122622979	7243_1:0031e4

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Annotation

OrthoDB (Group)

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Acknowledgements