GlyCosmos Portal

Displaying **all 5** entries
GO Term	Evidence Code	PMID
acetyl-CoA carboxylase activity	IBA IDA ISS TAS	20457939 20952656 26976583 29899443
metal ion binding	IEA
ATP binding	IEA
protein binding	IPI	16326698 16794074 18056116 19343720 20457939 20952656 29899443
identical protein binding	IPI	20457939

GO Hierarchy

molecular function

catalytic activity [inference]

ligase activity [inference]

ligase activity, forming carbon-carbon bonds [inference]

CoA carboxylase activity [inference]

acetyl-CoA carboxylase activity

binding [inference]

protein binding

identical protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000278540

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K11262

Name

acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]

References

Rhea

RHEA:11308

hydrogencarbonate + ATP + acetyl-CoA

H⁺ + phosphate + ADP + malonyl-CoA

Enzyme

6.4.1.2

PMID

Disease

Disease Ontology

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DO ID	Disease Name	Source
DOID:9970	obesity	DisGeNET

The Human Phenotype Ontology

Displaying **all 6** entries
HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0001252	Hypotonia
HP:0001263	Global developmental delay
HP:0001510	Growth delay
HP:0002151	Increased circulating lactate concentration
HP:0003198	Myopathy

Displaying 1 entry
Disease ID	Disease Name
OMIM:613933	acetyl-coa carboxylase deficiency

PubChem Disease

MedGen Diseases

Acetyl-CoA: carboxylase deficiency

OMIM Phenotypes

ACETYL-CoA CARBOXYLASE-ALPHA DEFICIENCY; ACACAD

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP006646
Gene Name: acetyl-CoA carboxylase alpha

Ortholog

Displaying entries **41 - 50** of 82 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Equus caballus	100071472		HORSE04467
Sus scrofa	397324		PIGXX02776
Bos taurus	281590		BOVIN12224
Capra hircus	100861224		CAPHI09969
Ovis aries	443186		SHEEP02452
Oryctolagus cuniculus	100355970		RABIT07482
Dipodomys ordii	105983462		DIPOR08505
Mus musculus	107476	MGI:108451	MOUSE05854
Rattus norvegicus	60581	RGD:621248	RATNO00862
Cavia porcellus	100733410		CAVPO13992

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

KEGG BRITE Database

PubChem Disease

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements