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sevenless

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

32039

PubChem

32039

Alliance of Genome Resources

FB:FBgn0003366

Annotation

Keyword

3D-structure
ATP-binding
Cell membrane
Glycoprotein
Phosphoprotein
Receptor
Reference proteome
Repeat
Transmembrane helix
Tyrosine-protein kinase
Vision

Proteins

Displaying 1 entry
UniProt	Protein Name
P13368

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway	IBA
transmembrane receptor protein tyrosine kinase signaling pathway	IEA
R7 cell fate commitment	IMP	17985474 2004416 20980384 2882603 2882857
visual perception

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

sevenless signaling pathway

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular developmental process [inference]

cell fate commitment [inference]

neuron fate commitment [inference]

photoreceptor cell fate commitment [inference]

eye photoreceptor cell fate commitment [inference]

compound eye photoreceptor fate commitment [inference]

R7 cell fate commitment

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

germ-line stem-cell niche homeostasis

developmental process [inference]

cellular developmental process [inference]

cell fate commitment [inference]

neuron fate commitment [inference]

photoreceptor cell fate commitment [inference]

eye photoreceptor cell fate commitment [inference]

compound eye photoreceptor fate commitment [inference]

R7 cell fate commitment

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

germ-line stem-cell niche homeostasis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of TOR signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of TOR signaling

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein tyrosine kinase signaling pathway

sevenless signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of TOR signaling

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	IDA	2682647 7680109
plasma membrane	IBA
membrane	IEA
receptor complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
transmembrane receptor protein tyrosine kinase activity	IBA
transmembrane receptor protein tyrosine kinase activity	IEA
protein binding	IPI	1857416 7781603 8462098 9671493
ATP binding	IEA
boss receptor activity	IDA	7680109 9472002

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

catalytic activity, acting on a protein [inference]

protein kinase activity [inference]

protein tyrosine kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity

transmembrane receptor protein tyrosine kinase activity

boss receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

proto-oncogene tyrosine-protein kinase ros

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
ATP binding
nucleotide binding
regulation of TOR signaling
transmembrane receptor protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase signaling pathway

Displaying entries **1 - 10** of 12 in total

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InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin-like fold
LDLR class B repeat
Protein kinase domain
Protein kinase, ATP binding site
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Six-bladed beta-propeller, TolB-like
Tyrosine-protein kinase, active site