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vacuolar protein sorting 13C

Summary

Gene Symbol

Vps13c

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

320528

PubChem

320528

Alliance of Genome Resources

MGI:2444207

Annotation

Keyword

Acetylation
Alternative splicing
Endoplasmic reticulum
Endosome
Lipid droplet
Lipid transport
Lysosome
Methylation
Mitochondrion outer membrane
Phosphoprotein
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A1ILG8
Q8BX70	Vacuolar protein sorting-associated protein 13C

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein retention in Golgi apparatus	IBA
response to insulin	IMP	27329800
mitochondrion organization	IBA IEA ISO
lipid transport	IEA
negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization	ISO ISS

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

protein retention in Golgi apparatus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

response to stimulus [inference]

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone [inference]

response to insulin

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone [inference]

response to insulin

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of localization [inference]

transport [inference]

organic substance transport [inference]

lipid transport

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

maintenance of location [inference]

maintenance of protein location [inference]

maintenance of protein location in cell [inference]

protein retention in Golgi apparatus

maintenance of location in cell [inference]

maintenance of protein location in cell [inference]

protein retention in Golgi apparatus

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

protein localization to vacuole [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

establishment of protein localization [inference]

protein targeting [inference]

protein targeting to vacuole

establishment of protein localization to organelle [inference]

establishment of protein localization to vacuole [inference]

protein targeting to vacuole

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of catabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

negative regulation of response to stimulus [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of response to stimulus [inference]

negative regulation of response to stimulus [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular catabolic process [inference]

regulation of autophagy [inference]

regulation of macroautophagy [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

negative regulation of cellular process [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

regulation of mitochondrion organization [inference]

regulation of autophagy of mitochondrion [inference]

regulation of mitophagy [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

regulation of cellular response to stress [inference]

regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization [inference]

negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
late endosome	ISO ISS
endoplasmic reticulum membrane	ISO ISS
mitochondrial outer membrane	IEA ISO
late endosome membrane	IEA
lysosome	ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

outer membrane [inference]

organelle outer membrane [inference]

mitochondrial outer membrane

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

secretory granule membrane [inference]

dense core granule membrane

mitochondrial membrane [inference]

mitochondrial outer membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane

secretory granule membrane [inference]

dense core granule membrane

organelle outer membrane [inference]

mitochondrial outer membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

lipid droplet

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular non-membrane-bounded organelle [inference]

lipid droplet

Displaying 1 entry
GO Term	Evidence Code	PMID
molecular_function	ND

GO Hierarchy

molecular function

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Vacuolar protein sorting-associated protein 13

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
L: Replication, recombination and repair

Displaying **all 4** entries
Gene Ontology
lipid transport
mitochondrion organization
protein retention in Golgi apparatus
protein targeting to vacuole

Displaying **all 7** entries
InterPro
Atg2/VPS13, C-terminal
VPS13, middle RBG modules
Vacuolar protein sorting-associated protein 13, DH-like domain
Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain
Vacuolar protein sorting-associated protein 13, extended chorein
Vacuolar protein sorting-associated protein 13-like, N-terminal domain
Vacuolar protein sorting-associated protein 13

Disease

Disease Ontology

Displaying **all 6** entries
DO ID	Disease Name	Source
DOID:0050753	cerebellar ataxia	Alliance of Genome Resources
DOID:0050766	choreaacanthocytosis	Alliance of Genome Resources
DOID:0060896	Parkinson's disease 23	Alliance of Genome Resources
DOID:0111590	Cohen syndrome	Alliance of Genome Resources
DOID:0111611	autosomal recessive spinocerebellar ataxia 4	Alliance of Genome Resources
DOID:14330	Parkinson's disease	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of **117** in total

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Species	Gene ID	Orthologous MAtrix
Ornithorhynchus anatinus	100080158	ORNAN21314
Pongo abelii	100171773	PONAB08947
Taeniopygia guttata	100219644	TAEGU02159
Oryctolagus cuniculus	100355887	RABIT06007
Callithrix jacchus	100391369	CALJA01615
Ailuropoda melanoleuca	100476083	AILME06402
Anolis carolinensis	100561914	ANOCA14078
Nomascus leucogenys	100589508	NOMLE31863
Sus scrofa	100625505	PIGXX14185
Cavia porcellus	100725506	CAVPO21925