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multiple edematous wings

Summary

Gene Symbol

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

32275

PubChem

32275

Alliance of Genome Resources

FB:FBgn0004456

Annotation

Keyword

Alternative splicing
Cell adhesion
Cell membrane
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Glycoprotein
Integrin
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
X2JDJ5
Q24247	Position-specific antigen subunit alpha-1 Protein multiple edematous wings

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 28 in total

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GO Term	Evidence Code	PMID
actin filament organization	IMP	19903692
cell adhesion	IMP	7750648
cell adhesion	IEA
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	TAS	10908592
cell-matrix adhesion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cell-substrate adhesion [inference]

cell adhesion mediated by integrin

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

cell recognition [inference]

neuron recognition [inference]

axonal defasciculation

cellular developmental process [inference]

cell differentiation

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

supramolecular fiber organization [inference]

actin filament organization

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of chemical stimulus [inference]

sensory perception of smell

pattern specification process [inference]

regionalization [inference]

formation of animal organ boundary [inference]

salivary gland boundary specification

muscle attachment

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of epithelial integrity, open tracheal system

developmental process [inference]

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

apposition of dorsal and ventral imaginal disc-derived wing surfaces

post-embryonic appendage morphogenesis [inference]

imaginal disc-derived wing morphogenesis

animal organ morphogenesis [inference]

gland morphogenesis [inference]

salivary gland morphogenesis

appendage morphogenesis [inference]

imaginal disc-derived appendage morphogenesis [inference]

imaginal disc-derived wing morphogenesis

post-embryonic appendage morphogenesis [inference]

imaginal disc-derived wing morphogenesis

tissue morphogenesis [inference]

ectodermal digestive tract development [inference]

ectodermal digestive tract morphogenesis

anatomical structure formation involved in morphogenesis [inference]

formation of anatomical boundary [inference]

formation of animal organ boundary [inference]

salivary gland boundary specification

anatomical structure development [inference]

tube development [inference]

digestive tract development [inference]

midgut development

animal organ development [inference]

gland development [inference]

salivary gland development

cellular developmental process [inference]

cell differentiation

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of epithelial integrity, open tracheal system

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

integrin-mediated signaling pathway

regulation of biological quality [inference]

regulation of tube architecture, open tracheal system [inference]

maintenance of epithelial integrity, open tracheal system

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
plasma membrane	IDA	7972082
focal adhesion	IDA	19903692
integrin complex	ISS	10936444
integrin complex	NAS	14519396
integrin complex	IDA	7972082

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

protein complex involved in cell adhesion [inference]

integrin complex

membrane protein complex [inference]

plasma membrane protein complex [inference]

plasma membrane signaling receptor complex [inference]

integrin complex

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

lateral plasma membrane

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

side of membrane [inference]

external side of plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
integrin binding	IBA
protein heterodimerization activity	IPI	7972082
cell adhesion molecule binding	IMP	7750648
extracellular matrix binding	IDA	7972082

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

integrin binding

protein dimerization activity [inference]

protein heterodimerization activity

cell adhesion molecule binding

integrin binding

protein-containing complex binding [inference]

integrin binding

extracellular matrix binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

integrin

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 4** entries
Gene Ontology
cell adhesion mediated by integrin
cell-matrix adhesion
integrin binding
integrin-mediated signaling pathway

Displaying **all 9** entries
InterPro
FG-GAP repeat
Integrin alpha beta-propellor
Integrin alpha chain, C-terminal cytoplasmic region, conserved site
Integrin alpha chain
Integrin alpha, N-terminal
Integrin alpha, first immunoglubulin-like domain
Integrin alpha, second immunoglobulin-like domain
Integrin alpha, third immunoglobulin-like domain
Integrin domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 7** entries
Location	References
apical plasma membrane	PMID:19035354
integrin complex	PMID:7972082
basal plasma membrane	PMID:8898242
lateral plasma membrane	PMID:19035354
focal adhesion	PMID:19903692
membrane	FB:FBrf0231198
plasma membrane	PMID:7972082

Ortholog

Displaying **all 9** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus tropicalis	3655	Xenbase:XB-GENE-489982
Xenopus tropicalis	3675	Xenbase:XB-GENE-493979
Homo sapiens	3679	HGNC:6143
Xenopus tropicalis	16400	Xenbase:XB-GENE-493979
Xenopus tropicalis	16403	Xenbase:XB-GENE-489982
Homo sapiens	16404	HGNC:6143
Xenopus tropicalis	32275	Xenbase:XB-GENE-493979
Homo sapiens	81008	HGNC:6143
Xenopus tropicalis	176296	Xenbase:XB-GENE-493979

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements