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Guidelines

MIRAGE

Tyrosylprotein sulfotransferase

Summary

Gene Symbol

Tpst

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

32312

PubChem

32312

Alliance of Genome Resources

FB:FBgn0086674

Annotation

Keyword

Alternative splicing
Disulfide bond
Glycoprotein
Golgi apparatus
Reference proteome
Signal-anchor
Transferase
Transmembrane helix

Proteins

Displaying **all 4** entries
UniProt	Protein Name
M9PEH9
A8JUV2
Q9VYB7	Transport and Golgi organization protein 13 Tyrosylprotein sulfotransferase
M9PHI3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
peptidyl-tyrosine sulfation
protein secretion	IMP	16452979

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

sulfation [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

macromolecule modification [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

peptidyl-amino acid modification [inference]

peptidyl-tyrosine modification [inference]

peptidyl-tyrosine sulfation

cellular process [inference]

cellular metabolic process [inference]

sulfur compound metabolic process [inference]

sulfation [inference]

protein sulfation [inference]

peptidyl-tyrosine sulfation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

establishment of localization [inference]

transport [inference]

secretion [inference]

secretion by cell [inference]

protein secretion

organic substance transport [inference]

protein transport [inference]

protein secretion

nitrogen compound transport [inference]

protein transport [inference]

protein secretion

export from cell [inference]

secretion by cell [inference]

protein secretion

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

protein secretion

establishment of protein localization to extracellular region [inference]

protein secretion

protein localization to extracellular region [inference]

establishment of protein localization to extracellular region [inference]

protein secretion

Displaying **all 3** entries
GO Term	Evidence Code	PMID
Golgi membrane
Golgi apparatus	IDA	16452979
Golgi apparatus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein-tyrosine sulfotransferase activity	IDA	28211678
protein-tyrosine sulfotransferase activity	IBA
protein-tyrosine sulfotransferase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring sulphur-containing groups [inference]

sulfotransferase activity [inference]

protein-tyrosine sulfotransferase activity

catalytic activity, acting on a protein [inference]

protein-tyrosine sulfotransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

protein-tyrosine sulfotransferase A

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
protein-tyrosine sulfotransferase activity
transferase activity

Displaying **all 2** entries
InterPro
P-loop containing nucleoside triphosphate hydrolase
Protein-tyrosine sulfotransferase-like

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
Golgi apparatus	PMID:16452979
membrane	FB:FBrf0231198

Ortholog

Displaying **all 8** entries
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	8459	Xenbase:XB-GENE-962493
Xenopus tropicalis	8460	Xenbase:XB-GENE-953306
Xenopus tropicalis	22021	Xenbase:XB-GENE-953306
Xenopus tropicalis	22022	Xenbase:XB-GENE-962493
Xenopus tropicalis	30677	Xenbase:XB-GENE-953306
Xenopus tropicalis	32312	Xenbase:XB-GENE-962493
Xenopus tropicalis	176684	Xenbase:XB-GENE-962493
Xenopus tropicalis	288617	Xenbase:XB-GENE-953306

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025