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rumi

Summary

Gene Symbol

rumi

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

326122

KEGG Gene ID

dme:Dmel_CG31152

PubChem

326122

Alliance of Genome Resources

FB:FBgn0086253

Annotation

Keyword

3D-structure
Disulfide bond
Endoplasmic reticulum
Glycosyltransferase
Notch signaling pathway
Reference proteome
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A0B4KGR5
Q8T045

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
Notch signaling pathway
positive regulation of Notch signaling pathway	IBA IGI IMP	18243100 21771811 21965616 25378397 27807076
rhabdomere development	IMP	25412384
protein O-linked glycosylation	IBA IDA	21949356
negative regulation of Notch signaling pathway	IMP	18243100

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

protein O-linked glycosylation via serine

peptidyl-amino acid modification [inference]

peptidyl-serine modification [inference]

protein O-linked glycosylation via serine

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

cellular developmental process [inference]

cell fate commitment

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

rhabdomere development

developmental process [inference]

anatomical structure development [inference]

tissue development [inference]

muscle tissue development

cellular developmental process [inference]

cell fate commitment

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Notch signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of Notch signaling pathway [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of Notch signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Notch signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum lumen	IDA	18243100
endomembrane system	HDA IBA	19317464

GO Hierarchy

cellular component

cellular anatomical entity [inference]

endomembrane system

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

endoplasmic reticulum lumen

Displaying **all 5** entries
GO Term	Evidence Code	PMID
glucosyltransferase activity	IDA	18243100
EGF-domain serine glucosyltransferase activity	IDA	21949356 22117070
EGF-domain serine xylosyltransferase activity	IDA	21949356
UDP-glucosyltransferase activity	IBA IDA	27428513
UDP-xylosyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

UDP-glucosyltransferase activity

EGF-domain serine glucosyltransferase activity

UDP-xylosyltransferase activity

EGF-domain serine xylosyltransferase activity

hexosyltransferase activity [inference]

glucosyltransferase activity

UDP-glucosyltransferase activity

EGF-domain serine glucosyltransferase activity

pentosyltransferase activity [inference]

xylosyltransferase activity [inference]

UDP-xylosyltransferase activity

EGF-domain serine xylosyltransferase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

O-glucosyltransferase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
transferase activity

Displaying 1 entry
InterPro
Glycosyl transferase CAP10 domain

KEGG BRITE Database

Orthology

K13667

Name

EGF-domain serine glucosyl/xylosyltransferase [EC:2.4.1.376 2.4.2.63]

References

Alliance of Genome Resources

Expression

Displaying **all 3** entries
Location	References
membrane	FB:FBrf0231198
endoplasmic reticulum lumen	PMID:18243100
endomembrane system	PMID:19317464

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0060256	Dowling-Degos disease	Alliance of Genome Resources
DOID:0080762	autosomal recessive limb-girdle muscular dystrophy type 2Z	Alliance of Genome Resources
DOID:0110274	autosomal recessive limb-girdle muscular dystrophy	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 42 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources
Homo sapiens	56983		HGNC:22954
Mus musculus	224143		MGI:2444232
Rattus norvegicus	288091		RGD:1306248
Danio rerio	641495		ZFIN:ZDB-GENE-051120-24
Drosophila pseudoobscura	4800928	7237_0:001f1a
Drosophila ananassae	6501062	7217_1:000315
Drosophila yakuba	6537806	7245_1:002ea3
Drosophila erecta	6554883	7220_1:000ada
Drosophila grimshawi	6567946	7222_1:001c30
Drosophila mojavensis	6575400	7230_1:001017