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aldehyde dehydrogenase 6 family member A1

Summary

Gene Symbol

ALDH6A1

Organism

Bos taurus (cattle)

External Links

NCBI Gene: 327692
KEGG Gene ID: bta:327692
PubChem: 327692

Annotation

Keyword

Acetylation
Direct protein sequencing
Mitochondrion
NAD
Oxidoreductase
Phosphoprotein
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q07536	Aldehyde dehydrogenase family 6 member A1 Malonate-semialdehyde dehydrogenase [acylating]

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
valine catabolic process	IEA	30032202
thymine catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

small molecule catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organic substance metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic substance catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

organic cyclic compound catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

organonitrogen compound catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

amino acid metabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

branched-chain amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid metabolic process [inference]

valine metabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

cellular catabolic process [inference]

organic acid catabolic process [inference]

carboxylic acid catabolic process [inference]

amino acid catabolic process [inference]

branched-chain amino acid catabolic process [inference]

valine catabolic process

alpha-amino acid catabolic process [inference]

valine catabolic process

cellular nitrogen compound catabolic process [inference]

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

heterocycle catabolic process [inference]

nucleobase catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

thymine metabolic process [inference]

thymine catabolic process

pyrimidine-containing compound catabolic process [inference]

pyrimidine nucleobase catabolic process [inference]

thymine catabolic process

Displaying 1 entry
GO Term	Evidence Code	PMID
mitochondrion	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 2** entries
GO Term	Evidence Code	PMID
malonate-semialdehyde dehydrogenase (acetylating) activity	IEA	30032202
methylmalonate-semialdehyde dehydrogenase (acylating, NAD) activity	IEA	22301074 30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor [inference]

Gene Ontology information from NCBI Gene and UniProt.

KEGG BRITE Database

Orthology

K00140

Name

malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]

References

Rhea

H₂O + CoA + NAD⁺ + 2-methyl-3-oxopropanoate

H⁺ + hydrogencarbonate + propanoyl-CoA + NADH

Enzyme

1.2.1.27

PMID

H₂O + 3-oxopropanoate + CoA + NAD⁺

H⁺ + hydrogencarbonate + acetyl-CoA + NADH

Enzyme

1.2.1.27

PMID

16332250

Ortholog

Displaying entries **91 - 95** of 95 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Propithecus coquereli	105819880		PROCO01317
Nannospalax galili	103747367		NANGA11407
Corvus moneduloides	116446135		CORMO22906
Carlito syrichta	103253958		CARSF19907
Strigops habroptila	115606054		STRHB09732

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.0.0

Last updated: August 19, 2024