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protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

Summary

Gene Symbol

Ppfia2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

327814

PubChem

327814

Alliance of Genome Resources

MGI:2443834

Annotation

Keyword

Cell projection
Coiled coil
Cytoplasm
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Synapse

Proteins

Displaying **all 3** entries
UniProt	Protein Name
F7CYX4
B8QI34
Q8BSS9	Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
synapse organization	IBA
regulation of dendritic spine development	ISS
regulation of dendritic spine development	ISO
regulation of dendritic spine morphogenesis	ISS
regulation of dendritic spine morphogenesis	ISO

GO Hierarchy

biological process

cellular process [inference]

cellular localization [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport

cytoskeleton-dependent intracellular transport [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell junction organization [inference]

synapse organization

localization [inference]

establishment of localization [inference]

transport [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport

cytoskeleton-dependent intracellular transport [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

establishment of localization in cell [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport

cytoskeleton-dependent intracellular transport [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

dense core granule transport [inference]

dense core granule cytoskeletal transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

dense core granule transport [inference]

dense core granule cytoskeletal transport

organelle localization [inference]

vesicle localization [inference]

secretory granule localization [inference]

dense core granule localization [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

dense core granule transport [inference]

dense core granule cytoskeletal transport

establishment of organelle localization [inference]

establishment of vesicle localization [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

dense core granule transport [inference]

dense core granule cytoskeletal transport

cellular localization [inference]

intracellular transport [inference]

cytosolic transport [inference]

dense core granule transport [inference]

dense core granule cytoskeletal transport

cytoskeleton-dependent intracellular transport [inference]

vesicle cytoskeletal trafficking [inference]

dense core granule cytoskeletal transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendritic spine morphogenesis

regulation of dendritic spine development

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendritic spine morphogenesis

regulation of synapse organization [inference]

regulation of postsynapse organization [inference]

regulation of dendritic spine morphogenesis

regulation of vesicle-mediated transport [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of secretion by cell [inference]

regulation of exocytosis [inference]

regulation of regulated secretory pathway [inference]

regulation of synaptic vesicle exocytosis

regulation of neurotransmitter secretion [inference]

regulation of synaptic vesicle exocytosis

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
synaptic vesicle	ISO
cell surface	IEA
axon	IEA
presynaptic membrane	ISO
dendritic spine	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol [inference]

cytosolic region [inference]

presynaptic cytosol

cell surface

membrane [inference]

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic membrane

cell junction [inference]

synapse

glutamatergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

neuron spine [inference]

dendritic spine

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

postsynaptic specialization

presynaptic active zone

postsynapse [inference]

dendritic spine

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	16186258 18054859 23791195
protein-containing complex binding	IDA	23791195
structural constituent of presynapse	ISO

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of synapse [inference]

structural constituent of presynapse

binding [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

liprin-alpha

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
synapse organization

Displaying **all 6** entries
InterPro
LAR-interacting protein, Liprin
Liprin-alpha, SAM domain repeat 1
Liprin-alpha, SAM domain repeat 2
Liprin-alpha, SAM domain repeat 3
Sterile alpha motif domain
Sterile alpha motif/pointed domain superfamily

Ortholog

Displaying entries **11 - 20** of 71 in total

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Species	Gene ID	Orthologous MAtrix
Danio rerio	566597	DANRE34254
Macaca mulatta	698065	MACMU03556
Ornithorhynchus anatinus	100073548	ORNAN06327
Pongo abelii	100174409	PONAB05381
Taeniopygia guttata	100224740	TAEGU09363
Callithrix jacchus	100396322	CALJA44551
Ailuropoda melanoleuca	100484751	AILME15323
Sus scrofa	100512281	PIGXX26847
Nomascus leucogenys	100579336	NOMLE00138
Loxodonta africana	100675539	LOXAF19713