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poly (ADP-ribose) polymerase family, member 4

Summary

Gene Symbol

Parp4

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

328417

PubChem

328417

Alliance of Genome Resources

MGI:2685589

Annotation

Keyword

Cytoplasm
Glycosyltransferase
Methylation
NAD
Nucleotidyltransferase
Nucleus
Phosphoprotein
Reference proteome
Ribonucleoprotein

Proteins

Displaying 1 entry
UniProt	Protein Name
E9PYK3	ADP-ribosyltransferase diphtheria toxin-like 4 Poly [ADP-ribose] polymerase 4 Vault poly(ADP-ribose) polymerase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
inflammatory response	ISO
protein modification process	ISO
telomere maintenance via telomerase	IGI	15169895
regulation of telomerase activity	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

protein metabolic process [inference]

protein modification process

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

protein metabolic process [inference]

protein modification process

macromolecule modification [inference]

protein modification process

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

organic cyclic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

aromatic compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular nitrogen compound biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

heterocycle biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

DNA biosynthetic process [inference]

RNA-templated DNA biosynthetic process [inference]

telomere maintenance via telomerase

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

chromosome organization [inference]

telomere organization [inference]

telomere maintenance [inference]

telomere maintenance via telomere lengthening [inference]

telomere maintenance via telomerase

response to stimulus [inference]

response to stress [inference]

defense response [inference]

inflammatory response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of DNA metabolic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of DNA metabolic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of DNA biosynthetic process [inference]

regulation of telomerase activity

regulation of molecular function [inference]

regulation of catalytic activity [inference]

regulation of transferase activity [inference]

regulation of telomerase activity

Displaying entries **1 - 5** of 7 in total

1

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GO Term	Evidence Code	PMID
nucleus	TAS	15169895
cytosol	ISO
ribonucleoprotein complex	IEA
cytoplasm	IBA ISO
spindle	TAS	15169895

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

spindle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

spindle microtubule

Displaying entries **1 - 5** of 6 in total

1

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GO Term	Evidence Code	PMID
NAD+ ADP-ribosyltransferase activity	IBA ISO
glycosyltransferase activity	IEA
transferase activity	IEA
NAD+-protein ADP-ribosyltransferase activity	ISO
enzyme binding	ISO	15169895

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

glycosyltransferase activity

pentosyltransferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity

catalytic activity, acting on a protein [inference]

NAD+-protein ADP-ribosyltransferase activity

binding [inference]

protein binding [inference]

enzyme binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **11 - 20** of 46 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Macaca mulatta	717978		MACMU00044
Macaca mulatta	114669838		MACMU00044
Papio anubis	101019495		PAPAN11188
Mandrillus leucophaeus	105553791		MANLE08690
Pan paniscus	100980381		PANPA10861
Pan troglodytes	452486		PANTR07447
Pongo abelii	100172861		PONAB07152
Pongo abelii	100938826		PONAB07152
Homo sapiens	143	HGNC:271	HUMAN16559
Ailuropoda melanoleuca	100483457		AILME06148

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Last updated: August 19, 2024