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Dopamine 2-like receptor

Summary

Gene Symbol

Dop2R

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33007

PubChem

33007

Alliance of Genome Resources

FB:FBgn0053517

Annotation

Keyword

Alternative splicing
Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IS44

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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2

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GO Term	Evidence Code	PMID
G protein-coupled receptor signaling pathway	ISS	10908591
G protein-coupled receptor signaling pathway	IEA
dopamine receptor signaling pathway	IDA	12391323
anesthesia-resistant memory	IMP	27466338
positive regulation of MAPK cascade

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

dopamine receptor signaling pathway

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

memory [inference]

anesthesia-resistant memory

behavior [inference]

learning or memory [inference]

memory [inference]

anesthesia-resistant memory

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating G protein-coupled receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

adrenergic receptor signaling pathway [inference]

adenylate cyclase-activating adrenergic receptor signaling pathway

dopamine receptor signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

regulation of intracellular signal transduction [inference]

regulation of MAPK cascade [inference]

positive regulation of MAPK cascade

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of MAPK cascade

Displaying **all 5** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
membrane	ISS	10908591
membrane	NAS	12391323
membrane	IEA
synapse

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell junction [inference]

synapse

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
dopamine neurotransmitter receptor activity, coupled via Gi/Go	IDA	12391323
dopamine neurotransmitter receptor activity, coupled via Gi/Go	IBA
G protein-coupled receptor activity	ISS	10908591
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled amine receptor activity

neurotransmitter receptor activity [inference]

postsynaptic neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity [inference]

dopamine neurotransmitter receptor activity, coupled via Gi/Go

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

5-hydroxytryptamine receptor

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
G protein-coupled serotonin receptor signaling pathway
adenylate cyclase-inhibiting serotonin receptor signaling pathway
chemical synaptic transmission
neurotransmitter receptor activity
serotonin binding