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Collagen type IV alpha 1

Summary

Gene Symbol

Col4a1

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

33727

PubChem

33727

Alliance of Genome Resources

FB:FBgn0000299

Annotation

Keyword

3D-structure
Basement membrane
Collagen
Disulfide bond
Glycoprotein
Hydroxylation
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P08120	Collagen type IV alpha 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

1

2

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GO Term	Evidence Code	PMID
dorsal closure	TAS	10449347
extracellular matrix organization	IBA
post-embryonic digestive tract morphogenesis	IMP	26363084
cardiac muscle cell development	IMP	24935095
intestinal epithelial structure maintenance	IMP	26363084

GO Hierarchy

biological process

cellular process [inference]

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cellular component organization or biogenesis [inference]

cellular component organization [inference]

extracellular structure organization [inference]

extracellular matrix organization

basement membrane organization

external encapsulating structure organization [inference]

extracellular matrix organization

basement membrane organization

multicellular organismal process [inference]

system process [inference]

digestive system process [inference]

maintenance of gastrointestinal epithelium [inference]

intestinal epithelial structure maintenance

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium [inference]

intestinal epithelial structure maintenance

developmental process [inference]

anatomical structure morphogenesis [inference]

post-embryonic animal morphogenesis [inference]

post-embryonic digestive tract morphogenesis

embryonic morphogenesis [inference]

morphogenesis of embryonic epithelium [inference]

dorsal closure

tissue morphogenesis [inference]

morphogenesis of an epithelium [inference]

morphogenesis of embryonic epithelium [inference]

dorsal closure

anatomical structure development [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

cellular developmental process [inference]

cell development [inference]

muscle cell development [inference]

cardiac muscle cell development

cardiac cell development [inference]

cardiac muscle cell development

homeostatic process [inference]

multicellular organismal-level homeostasis [inference]

anatomical structure homeostasis [inference]

tissue homeostasis [inference]

epithelial structure maintenance [inference]

maintenance of gastrointestinal epithelium [inference]

intestinal epithelial structure maintenance

Displaying **all 5** entries
GO Term	Evidence Code	PMID
collagen trimer	IEA
collagen type IV trimer	TAS	7760738
basement membrane	IDA	12051824 18331716 27404358 28653906
extracellular space	IBA
collagen-containing extracellular matrix	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

collagen trimer

network-forming collagen trimer [inference]

collagen type IV trimer

basement membrane collagen trimer [inference]

collagen type IV trimer

cellular anatomical entity [inference]

extracellular space

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

basement membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular matrix structural constituent	IMP	28653906
extracellular matrix structural constituent	IEA
extracellular matrix structural constituent conferring tensile strength	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

extracellular matrix structural constituent

extracellular matrix structural constituent conferring tensile strength

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

collagen

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
extracellular matrix structural constituent conferring tensile strength
extracellular matrix structural constituent

Displaying **all 4** entries
InterPro
C-type lectin fold
Collagen IV, non-collagenous domain superfamily
Collagen IV, non-collagenous
Collagen triple helix repeat

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
basement membrane	PMID:12051824 PMID:18331716 PMID:27404358 PMID:28653906
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:423	myopathy	Alliance of Genome Resources
DOID:854	collagen disease	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements