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P-glycoprotein-1

Summary

Gene Symbol

EHI_114150

Organism

Entamoeba histolytica HM-1:IMSS

External Links

NCBI Gene: 3406078
PubChem: 3406078

Annotation

Keyword

ATP-binding
Glycoprotein
Reference proteome
Repeat
Translocase
Transmembrane helix
Transport

Proteins

Displaying 1 entry
UniProt	Protein Name
P16875	P-glycoprotein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
transmembrane transport	IEA	22301074

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

transmembrane transport

Displaying 1 entry
GO Term	Evidence Code	PMID
membrane	IEA	22301074

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

Displaying **all 3** entries
GO Term	Evidence Code	PMID
ABC-type transporter activity	IEA	22301074
ATP hydrolysis activity	IEA	22301074
ATP binding	IEA	22301074

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

transporter activity [inference]

transmembrane transporter activity [inference]

active transmembrane transporter activity [inference]

primary active transmembrane transporter activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

ATPase-coupled transmembrane transporter activity [inference]

ABC-type transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ABC

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
ABC-type transporter activity
ATP binding
nucleotide binding

Displaying **all 6** entries
InterPro
AAA+ ATPase domain
ABC transporter type 1, transmembrane domain superfamily
ABC transporter type 1, transmembrane domain
ABC transporter-like, ATP-binding domain
ABC transporter-like, conserved site
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **11 - 20** of 24 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Dictyostelium discoideum AX4	8629226	352472_0:003278
Dictyostelium purpureum	10502747	5786_0:0009e9
Dictyostelium purpureum	10504240	5786_0:001b68
Dictyostelium purpureum	10504284	5786_0:001ba0
Cavenderia fasciculata	14869462	261658_0:00208d
Cavenderia fasciculata	14872245	261658_0:0015b6
Entamoeba invadens IP1	14882728	370355_0:002d75
Entamoeba invadens IP1	14887135	370355_0:001c13
Entamoeba invadens IP1	14890584	370355_0:000ec5
Entamoeba invadens IP1	14891129	370355_0:000cc6

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Last updated: December 9, 2024