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R-spondin 4
Summary
- Gene Symbol
-
- RSPO4
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Disease variant
- Disulfide bond
- Glycoprotein
- Heparin-binding
- Phosphoprotein
- Reference proteome
- Secreted
- Sensory transduction
- Signal
- Wnt signaling pathway
- Proteins
| UniProt | Protein Name |
|---|---|
| Q2I0M5 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| Wnt signaling pathway | ||
| positive regulation of Wnt signaling pathway | ||
| positive regulation of Wnt signaling pathway | ||
| nail development | ||
| positive regulation of canonical Wnt signaling pathway |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| signaling receptor binding | ||
| protein binding | ||
| heparin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- R-spondin
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| heparin binding |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080082 | nonsyndromic congenital nail disorder 4 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 228770 | ZFIN:ZDB-GENE-110103-2 | MOUSE31027 | |
| 343637 | ZFIN:ZDB-GENE-110103-2 | ||
| 469857 | PANTR24190 | ||
| 499918 | RATNO26328 | ||
| 517783 | BOVIN04996 | ||
| 570865 | DANRE39201 | ||
| 715268 | MACMU02289 | ||
| 100067769 | HORSE21384 | ||
| 100226742 | TAEGU12038 | ||
| 100433882 | PONAB21003 |
