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interferon omega 1

Summary

Gene Symbol

IFNW1

Organism

Homo sapiens (human)

External Links

NCBI Gene

3467

PubChem

3467

Alliance of Genome Resources

HGNC:5448

JoGo

IFNW1

TogoVar

IFNW1

Annotation

Keyword

3D-structure
Antiviral defense
Cytokine
Direct protein sequencing
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P05000	Interferon alpha-II-1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
adaptive immune response	IBA
T cell activation involved in immune response	IBA
B cell activation involved in immune response	IBA
natural killer cell activation involved in immune response	IBA
humoral immune response	IBA

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interferon-mediated signaling pathway [inference]

type I interferon-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

response to nitrogen compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

interferon-mediated signaling pathway [inference]

type I interferon-mediated signaling pathway

regulation of cell cycle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IBA
receptor complex	IPI	21854986

GO Hierarchy

cellular component

protein-containing complex [inference]

receptor complex

cellular anatomical entity [inference]

extracellular space

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytokine activity	IBA
cytokine receptor binding	TAS	1647209
type I interferon receptor binding	IBA
protein binding	IPI	28514442 33961781

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

cytokine receptor binding

type I interferon receptor binding

receptor ligand activity [inference]

cytokine activity

protein-containing complex binding [inference]

type I interferon receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

interferon alpha-1

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
cytokine activity
cytokine receptor binding
defense response to virus
response to exogenous dsRNA

Displaying **all 2** entries
InterPro
Four-helical cytokine-like, core
Interferon alpha/beta/delta

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements