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Imaginal disc growth factor 2

Summary

Gene Symbol

Idgf2

Organism

Drosophila melanogaster (fruit fly)

External Links

NCBI Gene

34979

PubChem

34979

Alliance of Genome Resources

FB:FBgn0020415

Annotation

Keyword

3D-structure
Developmental protein
Disulfide bond
Glycoprotein
Proteomics identification
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9V3D4	Imaginal disk growth factor protein 2
D4G7B1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
positive regulation of cell population proliferation	IMP	28230183
chitin catabolic process	IBA
negative regulation of apoptotic process	IMP	28230183
imaginal disc development	IDA	9847235
carbohydrate metabolic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

amino sugar metabolic process [inference]

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

glucosamine-containing compound metabolic process [inference]

chitin metabolic process [inference]

chitin catabolic process

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

chitin metabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

carbohydrate derivative catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

amino sugar catabolic process [inference]

glucosamine-containing compound catabolic process [inference]

chitin catabolic process

organonitrogen compound catabolic process [inference]

aminoglycan catabolic process [inference]

chitin catabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

imaginal disc development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

regulation of cellular process [inference]

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of programmed cell death [inference]

regulation of apoptotic process [inference]

negative regulation of apoptotic process

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

negative regulation of cellular process [inference]

negative regulation of programmed cell death [inference]

negative regulation of apoptotic process

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IBA NAS	9847235
extracellular space	HDA IDA	15466469 28230183

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chitin binding	IEA
imaginal disc growth factor receptor binding	IDA	9847235

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

growth factor receptor binding [inference]

imaginal disc growth factor receptor binding

carbohydrate derivative binding [inference]

chitin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Chitinase A

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
chitin binding
chitin catabolic process
chitinase activity
hydrolase activity, acting on glycosyl bonds
hydrolase activity

Displaying **all 5** entries
InterPro
Chitinase II
Chitinase insertion domain superfamily
Glycoside hydrolase family 18, catalytic domain
Glycoside hydrolase superfamily
Glycosyl hydrolases family 18 (GH18) active site

Alliance of Genome Resources

Expression

Displaying **all 2** entries
Location	References
extracellular space	PMID:15466469 PMID:28230183
membrane	FB:FBrf0231198

Disease

Disease Ontology

Displaying entries **1 - 10** of 30 in total

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DO ID	Disease Name	Source
DOID:0050685	small cell carcinoma	Alliance of Genome Resources
DOID:0080199	colorectal carcinoma	Alliance of Genome Resources
DOID:10286	prostate carcinoma	Alliance of Genome Resources
DOID:10591	pre-eclampsia	Alliance of Genome Resources
DOID:10763	hypertension	Alliance of Genome Resources
DOID:11650	bronchopulmonary dysplasia	Alliance of Genome Resources
DOID:13375	temporal arteritis	Alliance of Genome Resources
DOID:13406	pulmonary sarcoidosis	Alliance of Genome Resources
DOID:1380	endometrial cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 57 in total

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Species	Gene ID	OrthoDB
Drosophila persimilis	6589345	7234_1:001edd
Drosophila sechellia	6614378	7238_1:000129
Drosophila sechellia	6614379	7238_0:00185c
Drosophila virilis	6627696	7244_1:0029fc
Drosophila willistoni	6643787	7260_0:001734
Drosophila simulans	6732520	7240_1:0006fa
Drosophila suzukii	108020907	28584_0:00072f
Drosophila suzukii	108021509	28584_0:000818
Drosophila biarmipes	108034436	125945_1:0008de
Drosophila rhopaloa	108049384	1041015_1:00257a

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OrthoDB (Group)

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Acknowledgements