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Guidelines

MIRAGE

c-24(28) sterol reductase

Summary

Gene Symbol

AFUA_5G14350

Organism

Aspergillus fumigatus Af293

External Links

NCBI Gene: 3511014
PubChem: 3511014

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
NADP
Oxidoreductase
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q4WW43	C-24(28) sterol reductase erg4A Ergosterol biosynthesis protein 4A Sterol Delta(24(28))-reductase erg4A

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
ergosterol biosynthetic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

secondary alcohol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

small molecule biosynthetic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

secondary alcohol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

sterol metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process [inference]

ergosterol biosynthetic process

phytosteroid biosynthetic process [inference]

ergosterol biosynthetic process

alcohol biosynthetic process [inference]

secondary alcohol biosynthetic process [inference]

ergosterol biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular lipid metabolic process [inference]

ergosterol metabolic process [inference]

ergosterol biosynthetic process

cellular lipid biosynthetic process [inference]

ergosterol biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying 1 entry
GO Term	Evidence Code	PMID
delta24(24-1) sterol reductase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the CH-CH group of donors [inference]

oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor [inference]

delta24(24-1) sterol reductase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

reductase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
lipid metabolic process
oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
oxidoreductase activity
steroid biosynthetic process
steroid metabolic process
sterol biosynthetic process

Displaying **all 2** entries
InterPro
Sterol biosynthesis ERG24/DHCR-like
Sterol reductase, conserved site

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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026