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autophagy related lipase Atg15, putative

Summary

Gene Symbol

AFUA_2G10900

Organism

Aspergillus fumigatus Af293

External Links

NCBI Gene: 3513512
PubChem: 3513512

Annotation

Keyword

Autophagy
Endosome
Glycoprotein
Hydrolase
Lipid degradation
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q4X180	Autophagy-related protein 15

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
multivesicular body membrane disassembly	IEA	30032202
piecemeal microautophagy of the nucleus	IEA	30032202
macroautophagy	IEA	30032202
neutral lipid catabolic process	IEA	30032202
phosphatidylserine catabolic process

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

neutral lipid catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

neutral lipid catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

neutral lipid catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

organic substance catabolic process [inference]

lipid catabolic process [inference]

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organonitrogen compound catabolic process [inference]

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular modified amino acid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

cellular modified amino acid catabolic process [inference]

phosphatidylserine catabolic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate metabolic process [inference]

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular catabolic process [inference]

autophagy [inference]

macroautophagy

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid metabolic process [inference]

neutral lipid metabolic process [inference]

neutral lipid catabolic process

phospholipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

cellular lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

neutral lipid catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid metabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylserine metabolic process [inference]

phosphatidylserine catabolic process

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

glycerolipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

phosphatidylserine catabolic process

process utilizing autophagic mechanism [inference]

autophagy [inference]

macroautophagy

nucleophagy [inference]

piecemeal microautophagy of the nucleus

microautophagy [inference]

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component disassembly [inference]

membrane disassembly [inference]

multivesicular body membrane disassembly

membrane organization [inference]

membrane disassembly [inference]

multivesicular body membrane disassembly

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane
vacuolar lumen
multivesicular body membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

bounding membrane of organelle [inference]

endosome membrane [inference]

late endosome membrane [inference]

multivesicular body membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen

Displaying **all 2** entries
GO Term	Evidence Code	PMID
triglyceride lipase activity
phospholipase activity	IEA	30032202

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

lipase activity [inference]

carboxylic ester hydrolase activity [inference]

triglyceride lipase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Lipase

Functional Category

E: Amino acid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
lipid metabolic process
multivesicular body membrane disassembly
neutral lipid catabolic process
phospholipase activity
piecemeal microautophagy of the nucleus

Displaying **all 2** entries
InterPro
Alpha/Beta hydrolase fold
Fungal lipase-like domain

Rhea

RHEA:12044

H₂O + a triacylglycerol

H⁺ + a diacylglycerol + a fatty acid

Enzyme

PMID

Ortholog

Displaying entries **1 - 10** of 48 in total

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Species	Gene ID	OrthoDB
Aspergillus nidulans FGSC A4	2870991	227321_0:000021
Aspergillus terreus NIH2624	4315897	341663_0:0021c5
Aspergillus fischeri NRRL 181	4587122	331117_0:000ecb
Aspergillus clavatus NRRL 1	4707621	344612_0:001f8c
Aspergillus nomiae NRRL 13137	26809517	1509407_0:001a35
Aspergillus aculeatus ATCC 16872	30970942	690307_0:000551
Aspergillus bombycis	34450831	109264_0:001a34
Aspergillus glaucus CBS 516.65	34465457	1160497_0:001bbb
Aspergillus candidus	36520130	41067_0:001508
Aspergillus novofumigatus IBT 16806	36535992	1392255_0:000098

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OrthoDB (Group)

International Collaboration

Acknowledgements