adenine phosphoribosyltransferase
| UniProt | Protein Name |
|---|---|
| P07741 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| purine ribonucleoside salvage | ||
| adenine salvage | ||
| grooming behavior | ||
| GMP salvage | ||
| IMP salvage |
| GO Term | Evidence Code | PMID |
|---|---|---|
| adenine binding | ||
| adenine phosphoribosyltransferase activity | ||
| adenine phosphoribosyltransferase activity | ||
| protein binding | ||
| AMP binding |
| Gene Ontology |
|---|
| AMP binding |
| AMP salvage |
| adenine binding |
| adenine phosphoribosyltransferase activity |
| adenine salvage |
| purine ribonucleoside salvage |
| transferase activity |
| InterPro |
|---|
| Adenine phosphoribosyl transferase |
| Phosphoribosyltransferase domain |
| Phosphoribosyltransferase-like |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060350 | adenine phosphoribosyltransferase deficiency |
| HPO ID | HPO Term |
|---|---|
| HP:0000007 | Autosomal recessive inheritance |
| HP:0000010 | Recurrent urinary tract infections |
| HP:0000016 | Urinary retention |
| HP:0000019 | Urinary hesitancy |
| HP:0000083 | Renal insufficiency |
| HP:0000093 | Proteinuria |
| HP:0000787 | Nephrolithiasis |
| HP:0000790 | Hematuria |
| HP:0000791 | Uric acid nephrolithiasis |
| HP:0000822 | Hypertension |
| Disease ID | Disease Name |
|---|---|
| ORPHA:976 |
|
| OMIM:614723 |
|
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: April 6, 2026