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zinc finger protein 445

Summary

Gene Symbol

ZNF445

Organism

Homo sapiens (human)

External Links

NCBI Gene

353274

PubChem

353274

Alliance of Genome Resources

HGNC:21018

JoGo

ZNF445

TogoVar

ZNF445

Annotation

Keyword

DNA-binding
Isopeptide bond
Nucleus
Proteomics identification
Reference proteome
Repeat
Transcription regulation
Ubl conjugation
Zinc-finger

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B7ZKX2
P59923	Zinc finger protein 168 Zinc finger protein with KRAB and SCAN domains 15

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
regulation of transcription by RNA polymerase II	IBA
negative regulation of gene expression via CpG island methylation	IMP	30602440
epigenetic programing of female pronucleus	IMP	30602440

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling [inference]

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of female pronucleus

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of female pronucleus

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of female pronucleus

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of female pronucleus

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

epigenetic regulation of gene expression [inference]

post-fertilization epigenetic regulation of gene expression [inference]

epigenetic programming in the zygotic pronuclei [inference]

epigenetic programing of female pronucleus

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of gene expression, epigenetic [inference]

negative regulation of gene expression via CpG island methylation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
nucleus	IDA	30602440
nucleus	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription activator activity, RNA polymerase II-specific
chromatin binding	IEA
protein binding	IPI	31413325 33961781
zinc ion binding	IEA